You are here

  • Home
  • Archive
  • Volume 65, Issue 12
  • Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice

Article info

Article menu
Download PDFPDF
Hepatology
Original article
Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice

Authors

  • Koen Vercauteren Department Clinical Chemistry, Microbiology and Immunology, Center for Vaccinology, Ghent University, Ghent, Belgium PubMed articlesGoogle scholar articles
  • Richard J P Brown Institute of Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research; a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Germany PubMed articlesGoogle scholar articles
  • Ahmed Atef Mesalam Department Clinical Chemistry, Microbiology and Immunology, Center for Vaccinology, Ghent University, Ghent, Belgium PubMed articlesGoogle scholar articles
  • Juliane Doerrbecker Institute of Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research; a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Germany PubMed articlesGoogle scholar articles
  • Sabin Bhuju Genome Analytics, Helmholtz Centre for Infection Research, Braunschweig, Germany PubMed articlesGoogle scholar articles
  • Robert Geffers Genome Analytics, Helmholtz Centre for Infection Research, Braunschweig, Germany PubMed articlesGoogle scholar articles
  • Naomi Van Den Eede Department Clinical Chemistry, Microbiology and Immunology, Center for Vaccinology, Ghent University, Ghent, Belgium PubMed articlesGoogle scholar articles
  • C Patrick McClure School of Life Sciences and the NIHR Nottingham Digestive Diseases Biomedical Research Unit, University of Nottingham, Queen's Medical Centre, Nottingham, UK PubMed articlesGoogle scholar articles
  • Fulvia Troise CEINGE, Naples, Italy PubMed articlesGoogle scholar articles
  • Lieven Verhoye Department Clinical Chemistry, Microbiology and Immunology, Center for Vaccinology, Ghent University, Ghent, Belgium PubMed articlesGoogle scholar articles
  • Thomas Baumert Institut National de la Santé et de la Recherche Médicale, U1110, Strasbourg, France Université de Strasbourg, Strasbourg et Pole Hépato-digestif, Hopitaux Universitaires de Strasbourg, Strasbourg, France PubMed articlesGoogle scholar articles
  • Ali Farhoudi Department Clinical Chemistry, Microbiology and Immunology, Center for Vaccinology, Ghent University, Ghent, Belgium PubMed articlesGoogle scholar articles
  • Riccardo Cortese CEINGE, Naples, Italy PubMed articlesGoogle scholar articles
  • Jonathan K Ball School of Life Sciences and the NIHR Nottingham Digestive Diseases Biomedical Research Unit, University of Nottingham, Queen's Medical Centre, Nottingham, UK PubMed articlesGoogle scholar articles
  • Geert Leroux-Roels Department Clinical Chemistry, Microbiology and Immunology, Center for Vaccinology, Ghent University, Ghent, Belgium PubMed articlesGoogle scholar articles
  • Thomas Pietschmann Institute of Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research; a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Germany German Centre for Infection Research (DZIF), Partner site Hannover-Braunschweig, Hannover, Germany PubMed articlesGoogle scholar articles
  • Alfredo Nicosia CEINGE, Naples, Italy Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Naples, Italy PubMed articlesGoogle scholar articles
  • Philip Meuleman Department Clinical Chemistry, Microbiology and Immunology, Center for Vaccinology, Ghent University, Ghent, Belgium PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Philip Meuleman, Department Clinical Chemistry, Microbiology and Immunology, Center for Vaccinology, Ghent University, UZ Gent, Building A, 1st floor, De Pintelaan 185, Gent B-9000, Belgium; philip.meuleman{at}ugent.be
View Full Text

Citation

Vercauteren K, Brown RJP, Mesalam AA, et al
Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice
Gut 2016;65:2029-2034.

Publication history

  • Received December 17, 2014
  • Revised July 22, 2015
  • Accepted July 23, 2015
  • First published August 25, 2015.
Online issue publication 
December 13, 2016

Article Versions

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Copyright information

Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/