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Prediction of oesophageal variceal bleeding by measuring spleen stiffness in patients with liver cirrhosis
  1. Yoshitaka Takuma1,2,
  2. Kazuhiro Nouso3,
  3. Youichi Morimoto2,
  4. Junko Tomokuni4,
  5. Akiko Sahara4,
  6. Hiroyuki Takabatake2,
  7. Akira Doi2,
  8. Kazuhiro Matsueda2,
  9. Hiroshi Yamamoto2
  1. 1 Department of Internal Medicine, Hiroshima City Hospital, Hiroshima, Japan
  2. 2 Department of Gastroenterology, Kurashiki Central Hospital, Okayama, Japan
  3. 3 Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan
  4. 4 Department of Laboratory Medicine, Kurashiki Central Hospital, Okayama, Japan
  1. Correspondence to Dr Yoshitaka Takuma, Department of Internal Medicine, Hiroshima City Hospital, 7-33 Motomachi, Naka-ku, Hiroshima, Hiroshima 730-8518, Japan; takuma{at}

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Letter to the Editor

We read with interest the guidelines by Tripathi et al 1 and the leading article by Rosselli et al,2 reporting the role of transient elastography for the diagnosis of oesophageal varices (OV).

Before screening endoscopy, non-invasive measures are needed to ascertain cirrhotic patients at high risk for oesophageal variceal bleeding (OVB) to decrease the number receiving unnecessary prophylactic treatments. In our recent study,3 spleen stiffness (SS) evaluated by acoustic radiation force impulse (ARFI) imaging was shown to be closely correlated with the presence of OV. This study aimed to evaluate SS determined by ARFI imaging as a predictor of OVB. We measured SS in 446 cirrhotic patients and followed them prospectively at Kurashiki Central Hospital between 2010 and 2014. We examined the diagnostic accuracy of SS for predicting OVB …

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  • Contributors The study was designed by YT. Data were obtained by YM, JT, AS, HT, AD, KM and HY. Data were analysed by YT. The report was written by YT and KN. All authors approved the final version.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; internally peer reviewed.