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Inflammatory bowel disease
Original article
Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease

Authors

  • E Quévrain Sorbonne Universités, UPMC Univ Paris 06, Paris, France INSERM-ERL 1157 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), CHU Saint-Antoine 27, Paris, France CNRS, UMR, Paris, France PubMed articlesGoogle scholar articles
  • M A Maubert Sorbonne Universités, UPMC Univ Paris 06, Paris, France INSERM-ERL 1157 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), CHU Saint-Antoine 27, Paris, France CNRS, UMR, Paris, France Département PM2 Plateforme de Métabolomique, APHP, Hôpital Saint Antoine, Peptidomique et dosage de Médicaments, Paris, France PubMed articlesGoogle scholar articles
  • C Michon INRA, UMR1319 Micalis, Jouy-en-Josas, France AgroParisTech, UMR Micalis, Jouy-en-Josas, France PubMed articlesGoogle scholar articles
  • F Chain INRA, UMR1319 Micalis, Jouy-en-Josas, France AgroParisTech, UMR Micalis, Jouy-en-Josas, France PubMed articlesGoogle scholar articles
  • R Marquant Sorbonne Universités, UPMC Univ Paris 06, Paris, France CNRS, UMR, Paris, France Département de Chimie 24 rue Lhomond, Ecole Normale Supérieure- PSL Research University, Paris, France PubMed articlesGoogle scholar articles
  • J Tailhades Sorbonne Universités, UPMC Univ Paris 06, Paris, France CNRS, UMR, Paris, France Département de Chimie 24 rue Lhomond, Ecole Normale Supérieure- PSL Research University, Paris, France PubMed articlesGoogle scholar articles
  • S Miquel INRA, UMR1319 Micalis, Jouy-en-Josas, France AgroParisTech, UMR Micalis, Jouy-en-Josas, France PubMed articlesGoogle scholar articles
  • L Carlier Sorbonne Universités, UPMC Univ Paris 06, Paris, France CNRS, UMR, Paris, France Département de Chimie 24 rue Lhomond, Ecole Normale Supérieure- PSL Research University, Paris, France PubMed articlesGoogle scholar articles
  • L G Bermúdez-Humarán INRA, UMR1319 Micalis, Jouy-en-Josas, France AgroParisTech, UMR Micalis, Jouy-en-Josas, France PubMed articlesGoogle scholar articles
  • B Pigneur Sorbonne Universités, UPMC Univ Paris 06, Paris, France INSERM-ERL 1157 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), CHU Saint-Antoine 27, Paris, France CNRS, UMR, Paris, France PubMed articlesGoogle scholar articles
  • O Lequin Sorbonne Universités, UPMC Univ Paris 06, Paris, France CNRS, UMR, Paris, France Département de Chimie 24 rue Lhomond, Ecole Normale Supérieure- PSL Research University, Paris, France PubMed articlesGoogle scholar articles
  • P Kharrat INRA, UMR1319 Micalis, Jouy-en-Josas, France AgroParisTech, UMR Micalis, Jouy-en-Josas, France PubMed articlesGoogle scholar articles
  • G Thomas Sorbonne Universités, UPMC Univ Paris 06, Paris, France INSERM-ERL 1157 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), CHU Saint-Antoine 27, Paris, France CNRS, UMR, Paris, France PubMed articlesGoogle scholar articles
  • D Rainteau Sorbonne Universités, UPMC Univ Paris 06, Paris, France INSERM-ERL 1157 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), CHU Saint-Antoine 27, Paris, France CNRS, UMR, Paris, France Département PM2 Plateforme de Métabolomique, APHP, Hôpital Saint Antoine, Peptidomique et dosage de Médicaments, Paris, France PubMed articlesGoogle scholar articles
  • C Aubry INRA, UMR1319 Micalis, Jouy-en-Josas, France AgroParisTech, UMR Micalis, Jouy-en-Josas, France PubMed articlesGoogle scholar articles
  • N Breyner INRA, UMR1319 Micalis, Jouy-en-Josas, France AgroParisTech, UMR Micalis, Jouy-en-Josas, France PubMed articlesGoogle scholar articles
  • C Afonso Université de Rouen, UMR 6014 COBRA/IRCOF, Mont Saint Aignan, France PubMed articlesGoogle scholar articles
  • S Lavielle Sorbonne Universités, UPMC Univ Paris 06, Paris, France CNRS, UMR, Paris, France Département de Chimie 24 rue Lhomond, Ecole Normale Supérieure- PSL Research University, Paris, France PubMed articlesGoogle scholar articles
  • J-P Grill Sorbonne Universités, UPMC Univ Paris 06, Paris, France INSERM-ERL 1157 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), CHU Saint-Antoine 27, Paris, France CNRS, UMR, Paris, France PubMed articlesGoogle scholar articles
  • G Chassaing Sorbonne Universités, UPMC Univ Paris 06, Paris, France CNRS, UMR, Paris, France Département de Chimie 24 rue Lhomond, Ecole Normale Supérieure- PSL Research University, Paris, France PubMed articlesGoogle scholar articles
  • J M Chatel INRA, UMR1319 Micalis, Jouy-en-Josas, France AgroParisTech, UMR Micalis, Jouy-en-Josas, France PubMed articlesGoogle scholar articles
  • G Trugnan Sorbonne Universités, UPMC Univ Paris 06, Paris, France INSERM-ERL 1157 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), CHU Saint-Antoine 27, Paris, France CNRS, UMR, Paris, France Département PM2 Plateforme de Métabolomique, APHP, Hôpital Saint Antoine, Peptidomique et dosage de Médicaments, Paris, France PubMed articlesGoogle scholar articles
  • R Xavier Center for Systems Biology, Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • P Langella INRA, UMR1319 Micalis, Jouy-en-Josas, France AgroParisTech, UMR Micalis, Jouy-en-Josas, France PubMed articlesGoogle scholar articles
  • H Sokol Sorbonne Universités, UPMC Univ Paris 06, Paris, France INSERM-ERL 1157 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), CHU Saint-Antoine 27, Paris, France CNRS, UMR, Paris, France INRA, UMR1319 Micalis, Jouy-en-Josas, France Service de Gastroentérologie et nutrition, APHP, Hôpital Saint Antoine, Paris, France PubMed articlesGoogle scholar articles
  • P Seksik Sorbonne Universités, UPMC Univ Paris 06, Paris, France INSERM-ERL 1157 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), CHU Saint-Antoine 27, Paris, France CNRS, UMR, Paris, France Service de Gastroentérologie et nutrition, APHP, Hôpital Saint Antoine, Paris, France PubMed articlesGoogle scholar articles
  1. Correspondence to Dr P Seksik, Service de Gastroentérologie et Nutrition, Hôpital St-Antoine, 184 rue du Faubourg St-Antoine, Paris 75571, Cedex 12, France; philippe.seksik{at}sat.aphp.fr
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Citation

Quévrain E, Maubert MA, Michon C, et al
Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease
Gut 2016;65:415-425.

Publication history

  • Received May 13, 2014
  • Revised May 19, 2015
  • Accepted May 21, 2015
  • First published June 4, 2015.
Online issue publication 
February 12, 2016

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