Article Text

Download PDFPDF
Lead time bias in estimating survival outcomes
  1. Antonio Facciorusso1,
  2. Jose Ferrusquía2,
  3. Nicola Muscatiello1
  1. 1 Gastroenterology Unit, Department of Medical Sciences, University of Foggia, Foggia, Italy
  2. 2 Gastroenterology and Hepatology Department, Central University Hospital of Asturias, Oviedo, Spain
  1. Correspondence to Dr Antonio Facciorusso, Gastroenterology Unit, Department of Medical Sciences, University of Foggia, AOU Ospedali Riuniti, Viale Pinto, 1, Foggia 71100, Italy; antonio.facciorusso{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

We read with great interest the article by Govindarajan et al,1 whose aim was to compare the survival outcomes among patients with postcolonoscopy colon rectal cancer (PCCRC), patients with colonoscopy-detected cancers and those diagnosed with CRC with no prior colonoscopy.

In this very well written paper, patients with PCCRC showed inferior survival time than colonoscopy-detected cancers, probably due to more advanced stages at diagnosis, while the worse outcomes were observed in those patients with no recent …

View Full Text


  • Contributors AF is the guarantor of this article. AF and JF wrote the letter. NM revised the manuscript. All the authors approved the final draft submitted.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.