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Contributors HE, RW, UWD and JH acquired data. CC, LA and OC acquired data from the Paris cohort. SL calculated statistics. HE, CC, LA, OC, AWL and CS interpreted data. All authors approved the final manuscript.
Funding The study was supported by the Deutsche Forschungsgemeinschaft (SFB841 and KFO306), the YAEL-Foundation and the Helmut and Hannelore Greve Foundation.
Competing interests None declared.
Ethics approval Hamburg ethical review board (OB-17/06), Comité de protection des personnes, Ile de France V, 02/04/2013.
Provenance and peer review Not commissioned; internally peer reviewed.