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Contributors The Commentary text and figure were drafted by IA and MFN.
Competing interests M FN has provided expert scientific advice or received funding from Giuliani Pharma, PPD, Schering-Plough, Takeda, Essex, MSD, Janssen, Boehringer, UCB, Abbott/Abbvie and Pentax.
Provenance and peer review Commissioned; internally peer reviewed.
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