Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

Jun Yu; Qiang Feng; Sunny Hei Wong; Dongya Zhang; Qiao yi Liang; Youwen Qin; Longqing Tang; Hui Zhao; Jan Stenvang; Yanli Li; Xiaokai Wang; Xiaoqiang Xu; Ning Chen; William Ka Kei Wu; Jumana Al-Aama; Hans Jørgen Nielsen; Pia Kiilerich; Benjamin Anderschou Holbech Jensen; Tung On Yau; Zhou Lan; Huijue Jia; Junhua Li; Liang Xiao; Thomas Yuen Tung Lam; Siew Chien Ng; Alfred Sze-Lok Cheng; Vincent Wai-Sun Wong; Francis Ka Leung Chan; Xun Xu; Huanming Yang; Lise Madsen; Christian Datz; Herbert Tilg; Jian Wang; Nils Brünner; Karsten Kristiansen; Manimozhiyan Arumugam; Joseph Jao-Yiu Sung; Jun Wang

doi:10.1136/gutjnl-2015-309800

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Gut microbiota

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Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

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Jun Yu Department of Medicine & Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong PubMed articles Google scholar articles
Qiang Feng BGI-Shenzhen, Shenzhen, China Department of Biology, University of Copenhagen, Copenhagen, Denmark PubMed articles Google scholar articles
Sunny Hei Wong Department of Medicine & Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong PubMed articles Google scholar articles
Dongya Zhang BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Qiao yi Liang Department of Medicine & Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong PubMed articles Google scholar articles
Youwen Qin BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Longqing Tang BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Hui Zhao BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Jan Stenvang Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark PubMed articles Google scholar articles
Yanli Li BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Xiaokai Wang BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Xiaoqiang Xu BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Ning Chen BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
William Ka Kei Wu Department of Medicine & Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong PubMed articles Google scholar articles
Jumana Al-Aama BGI-Shenzhen, Shenzhen, China Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia PubMed articles Google scholar articles
Hans Jørgen Nielsen Department of Surgical Gastroenterology, Hvidovre Hospital, Hvidovre, Denmark PubMed articles Google scholar articles
Pia Kiilerich Department of Biology, University of Copenhagen, Copenhagen, Denmark PubMed articles Google scholar articles
Benjamin Anderschou Holbech Jensen Department of Biology, University of Copenhagen, Copenhagen, Denmark PubMed articles Google scholar articles
Tung On Yau Department of Medicine & Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong PubMed articles Google scholar articles
Zhou Lan BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Huijue Jia BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Junhua Li BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Liang Xiao BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Thomas Yuen Tung Lam Department of Medicine & Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong PubMed articles Google scholar articles
Siew Chien Ng Department of Medicine & Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong PubMed articles Google scholar articles
Alfred Sze-Lok Cheng Department of Medicine & Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong PubMed articles Google scholar articles
Vincent Wai-Sun Wong Department of Medicine & Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong PubMed articles Google scholar articles
Francis Ka Leung Chan Department of Medicine & Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong PubMed articles Google scholar articles
Xun Xu BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Huanming Yang BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Lise Madsen BGI-Shenzhen, Shenzhen, China Department of Biology, University of Copenhagen, Copenhagen, Denmark National Institute of Nutrition and Seafood Research, Bergen, Norway PubMed articles Google scholar articles
Christian Datz Department of Internal Medicine, Hospital Oberndorf, Q3 Teaching Hospital of the Paracelsus Private University of Salzburg, Oberndorf, Austria PubMed articles Google scholar articles
Herbert Tilg First Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Jian Wang BGI-Shenzhen, Shenzhen, China PubMed articles Google scholar articles
Nils Brünner BGI-Shenzhen, Shenzhen, China Department of Veterinary Disease Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark PubMed articles Google scholar articles
Karsten Kristiansen BGI-Shenzhen, Shenzhen, China Department of Biology, University of Copenhagen, Copenhagen, Denmark PubMed articles Google scholar articles
Manimozhiyan Arumugam BGI-Shenzhen, Shenzhen, China The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark PubMed articles Google scholar articles
Joseph Jao-Yiu Sung Department of Medicine & Therapeutics, State Key Laboratory of Digestive Disease, Institute of Digestive Disease, LKS Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong PubMed articles Google scholar articles
Jun Wang BGI-Shenzhen, Shenzhen, China Department of Biology, University of Copenhagen, Copenhagen, Denmark Princess Al Jawhara Center of Excellence in the Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia Macau University of Science and Technology, Macau, China PubMed articles Google scholar articles

Correspondence to Professor Jun Wang, Beijing Genomics Institute at Shenzhen, Shenzhen 518000, China; wangj{at}genomics.org.cn and Professor Joseph JY Sung, The Chinese University of Hong Kong, Hong Kong; jjysung{at}cuhk.edu.hk and Dr Manimozhiyan Arumugam, University of Copenhagen, 2200 Copenhagen, Denmark; arumugam{at}sund.ku.dk

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Citation

Yu J, Feng Q, Wong SH, et al

Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

Gut 2017;66:70-78.

Publication history

Received April 21, 2015
Revised August 26, 2015
Accepted September 1, 2015
First published September 25, 2015.

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July 07, 2018

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