Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma

Matthew F Buas; Qianchuan He; Lisa G Johnson; Lynn Onstad; David M Levine; Aaron P Thrift; Puya Gharahkhani; Claire Palles; Jesper Lagergren; Rebecca C Fitzgerald; Weimin Ye; Carlos Caldas; Nigel C Bird; Nicholas J Shaheen; Leslie Bernstein; Marilie D Gammon; Anna H Wu; Laura J Hardie; Paul D Pharoah; Geoffrey Liu; Prassad Iyer; Douglas A Corley; Harvey A Risch; Wong-Ho Chow; Hans Prenen; Laura Chegwidden; Sharon Love; Stephen Attwood; Paul Moayyedi; David MacDonald; Rebecca Harrison; Peter Watson; Hugh Barr; John deCaestecker; Ian Tomlinson; Janusz Jankowski; David C Whiteman; Stuart MacGregor; Thomas L Vaughan; Margaret M Madeleine

doi:10.1136/gutjnl-2016-311622

Article info

Oesophagus

Original article

Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma

Authors

Matthew F Buas Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA PubMed articles Google scholar articles
Qianchuan He Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA PubMed articles Google scholar articles
Lisa G Johnson Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA PubMed articles Google scholar articles
Lynn Onstad Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA PubMed articles Google scholar articles
David M Levine Department of Biostatistics, University of Washington, School of Public Health, Seattle, Washington, USA PubMed articles Google scholar articles
Aaron P Thrift Department of Medicine, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA PubMed articles Google scholar articles
Puya Gharahkhani Queensland Institute of Medical Research Berghofer Medical Research Institute Brisbane, Queensland, Australia PubMed articles Google scholar articles
Claire Palles Wellcome Trust Centre for Human Genetics and NIHR Comprehensive Biomedical Research Centre, University of Oxford, Oxford, UK PubMed articles Google scholar articles
Jesper Lagergren Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden Division of Cancer Studies, King's College London, UK PubMed articles Google scholar articles
Rebecca C Fitzgerald Medical Research Council (MRC) MRC Cancer Unit, Hutchison-MRC Research Centre, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Weimin Ye Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden PubMed articles Google scholar articles
Carlos Caldas Cancer Research UK, Cambridge Institute, Cambridge, UK PubMed articles Google scholar articles
Nigel C Bird Department of Oncology, Medical School, University of Sheffield, Sheffield, UK PubMed articles Google scholar articles
Nicholas J Shaheen Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA PubMed articles Google scholar articles
Leslie Bernstein Department of Population Sciences, Beckman Research Institute and City of Hope Comprehensive Cancer Center, Duarte, California, USA PubMed articles Google scholar articles
Marilie D Gammon Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA PubMed articles Google scholar articles
Anna H Wu Department of Preventive Medicine, University of Southern California/Norris Comprehensive Cancer Center, Los Angeles, California, USA PubMed articles Google scholar articles
Laura J Hardie Division of Epidemiology, University of Leeds, Leeds, UK PubMed articles Google scholar articles
Paul D Pharoah Department of Oncology, University of Cambridge, Cambridge, UK Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK PubMed articles Google scholar articles
Geoffrey Liu Pharmacogenomic Epidemiology, Ontario Cancer Institute, Toronto, Ontario, Canada PubMed articles Google scholar articles
Prassad Iyer Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA PubMed articles Google scholar articles
Douglas A Corley Division of Research, Kaiser Permanente Northern California, Oakland, California, USA San Francisco Medical Center, Kaiser Permanente Northern California, San Francisco, California, USA PubMed articles Google scholar articles
Harvey A Risch Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut, USA PubMed articles Google scholar articles
Wong-Ho Chow Department of Epidemiology, MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Hans Prenen Department of Digestive Oncology, University Hospital Gasthuisberg, Leuven, Belgium PubMed articles Google scholar articles
Laura Chegwidden University of Cambridge Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK PubMed articles Google scholar articles
Sharon Love Centre for Statistics in Medicine and Oxford Clinical Trials Research Unit, Oxford, UK PubMed articles Google scholar articles
Stephen Attwood Department of General Surgery, North Tyneside General Hospital, North Shields, UK PubMed articles Google scholar articles
Paul Moayyedi Department of Medicine, McMaster University, Hamilton, Ontario, Canada PubMed articles Google scholar articles
David MacDonald Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, British Columbia, Canada PubMed articles Google scholar articles
Rebecca Harrison Department of Pathology, Leicester Royal Infirmary, Leicester, UK PubMed articles Google scholar articles
Peter Watson Department of Medicine, Institute of Clinical Science, Royal Victoria Hospital, Belfast, UK PubMed articles Google scholar articles
Hugh Barr Department of Upper GI Surgery, Gloucestershire Royal Hospital, Gloucester, UK PubMed articles Google scholar articles
John deCaestecker Department of Gastroenterology, Leicester General Hospital, Leicester, UK PubMed articles Google scholar articles
Ian Tomlinson Wellcome Trust Centre for Human Genetics and NIHR Comprehensive Biomedical Research Centre, University of Oxford, Oxford, UK PubMed articles Google scholar articles
Janusz Jankowski UClan Medical School, West Lakes Campus, Rm 127 Lindow Centre, Cumbria, UK PubMed articles Google scholar articles
David C Whiteman Cancer Control, QIMR Berghofer Medical Research Institute, Brisbane, Australia PubMed articles Google scholar articles
Stuart MacGregor Queensland Institute of Medical Research Berghofer Medical Research Institute Brisbane, Queensland, Australia PubMed articles Google scholar articles
Thomas L Vaughan Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA Department of Epidemiology, University of Washington, School of Public Health, Seattle, Washington, USA PubMed articles Google scholar articles
Margaret M Madeleine Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA Department of Epidemiology, University of Washington, School of Public Health, Seattle, Washington, USA PubMed articles Google scholar articles

Correspondence to Professor Margaret M Madeleine, Department of Epidemiology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4-C308, Seattle, WA 98109, USA; mmadelei{at}fredhutch.org

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Citation

Buas MF, He Q, Johnson LG, et al

Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma

Gut 2017;66:1739-1747.

Publication history

Received February 9, 2016
Revised June 22, 2016
Accepted July 2, 2016
First published August 2, 2016.

Online issue publication

February 20, 2018

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