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  • MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47phox–oxidative stress pathway in neutrophils

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Hepatology
Original article
MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47phox–oxidative stress pathway in neutrophils

Authors

  • Man Li Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA Laboratory of Cellular Immunity, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Yong He Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Zhou Zhou Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Teresa Ramirez Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Yueqiu Gao Laboratory of Cellular Immunity, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Yanhang Gao Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Ruth A Ross Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA PubMed articlesGoogle scholar articles
  • Haixia Cao Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Yan Cai Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Mingjiang Xu Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Dechun Feng Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Ping Zhang Department of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, Ohio, USA PubMed articlesGoogle scholar articles
  • Suthat Liangpunsakul Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA Department of Biochemistry and Molecular Biology, Indiana University, Indianapolis, Indiana, USA Roudebush Veterans Administration Medical Center, Indianapolis, Indiana, USA PubMed articlesGoogle scholar articles
  • Bin Gao Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Bin Gao, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5625 Fishers Lane, Bethesda MD 20852, USA; bgao{at}mail.nih.gov, Dr Suthat Liangpunsakul, Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University, 550 University Blvd, Indianapolis, IN 46202, USA; sliangpu{at}iug.edu
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Citation

Li M, He Y, Zhou Z, et al
MicroRNA-223 ameliorates alcoholic liver injury by inhibiting the IL-6–p47phox–oxidative stress pathway in neutrophils
Gut 2017;66:705-715.

Publication history

  • Received March 14, 2016
  • Revised August 25, 2016
  • Accepted August 26, 2016
  • First published September 27, 2016.
Online issue publication 
October 26, 2017

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/