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We read with great interest the recent endoscopy news reported by Gluck et al,1 presenting a novel prepless X-ray imaging capsule for colon cancer screening. The capsule emits low-dose X-rays that can penetrate the colon contents and identify polyps without the need for bowel preparation. However, one capsule retention occurred in 46 asymptomatic volunteers in a pilot study and it was retrieved by colonoscopy. Actually, capsule endoscopy retention is not rare even in patient without suspected Crohn's disease or bowel obstruction, with a retention rate of around 1.0%.2 ,3 Most retained capsules remain harmless but some can cause bowel obstruction, perforation or even capsule fragmentation.4 Several case reports described the use of double-balloon enteroscopy (DBE) for capsule extraction.5 ,6
In this investigation, we aimed to evaluate the use of DBE for retrieval of endoscopic capsules and identify …
YW and ZLiao contributed equally.
Contributors YD and ZLi conceived and designed the study. ZLiao analysed and interpreted the data. YW wrote the draft. PW assisted with study design, and JC, JG, HF and YD provided clinical data.
Funding This investigation was supported by the grant from National Clinical Research Center for Digestive Diseases of China (2015BAI13B08).
Competing interests None declared.
Patient consent Obtained.
Ethics approval Shanghai Changhai Hospital Ethics Committee.
Provenance and peer review Not commissioned; internally peer reviewed.