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YW and ZLiao contributed equally.
Contributors YD and ZLi conceived and designed the study. ZLiao analysed and interpreted the data. YW wrote the draft. PW assisted with study design, and JC, JG, HF and YD provided clinical data.
Funding This investigation was supported by the grant from National Clinical Research Center for Digestive Diseases of China (2015BAI13B08).
Competing interests None declared.
Patient consent Obtained.
Ethics approval Shanghai Changhai Hospital Ethics Committee.
Provenance and peer review Not commissioned; internally peer reviewed.