Oral versus intravenous iron replacement therapy distinctly alters the gut microbiota and metabolome in patients with IBD

Thomas Lee; Thomas Clavel; Kirill Smirnov; Annemarie Schmidt; Ilias Lagkouvardos; Alesia Walker; Marianna Lucio; Bernhard Michalke; Philippe Schmitt-Kopplin; Richard Fedorak; Dirk Haller

doi:10.1136/gutjnl-2015-309940

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Inflammatory bowel disease

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Oral versus intravenous iron replacement therapy distinctly alters the gut microbiota and metabolome in patients with IBD

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May 2016	238	211	135
Jun 2016	150	150	91
Jul 2016	167	140	74
Aug 2016	145	140	68
Sep 2016	179	231	79
Oct 2016	181	205	74
Nov 2016	196	178	84
Dec 2016	150	124	48
Jan 2017	237	156	80
Feb 2017	90	148	107
Mar 2017	19	247	57
Apr 2017	25	813	211
May 2017	5	615	172
Jun 2017	82	328	106
Jul 2017	335	312	110
Aug 2017	360	311	89
Sep 2017	894	722	136
Oct 2017	512	403	93
Nov 2017	505	413	110
Dec 2017	513	403	123
Jan 2018	640	522	149
Feb 2018	489	356	116
Mar 2018	467	357	95
Apr 2018	389	321	78
May 2018	452	386	111
Jun 2018	389	334	49
Jul 2018	306	250	57
Aug 2018	233	194	62
Sep 2018	265	225	42
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Nov 2018	231	228	56
Dec 2018	142	138	37
Jan 2019	194	191	63
Feb 2019	169	168	44
Mar 2019	219	215	70
Apr 2019	226	219	63
May 2019	187	184	77
Jun 2019	205	203	54
Jul 2019	274	225	79
Aug 2019	241	207	86
Sep 2019	198	168	56
Oct 2019	286	209	84
Nov 2019	274	219	116
Dec 2019	232	180	77
Jan 2020	260	205	93
Feb 2020	222	177	65
Mar 2020	184	157	90
Apr 2020	191	146	97
May 2020	174	124	166
Jun 2020	205	181	146
Jul 2020	191	141	74
Aug 2020	165	139	94
Sep 2020	237	178	159
Oct 2020	222	187	99
Nov 2020	183	149	90
Dec 2020	183	162	60
Jan 2021	223	195	78
Feb 2021	167	147	73
Mar 2021	241	189	96
Apr 2021	226	191	123
May 2021	215	189	98
Jun 2021	151	153	73
Jul 2021	168	170	66
Aug 2021	174	173	48
Sep 2021	165	162	76
Oct 2021	238	195	137
Nov 2021	209	163	119
Dec 2021	209	172	83
Jan 2022	187	174	82
Feb 2022	405	379	84
Mar 2022	272	249	120
Apr 2022	286	263	103
May 2022	313	286	94
Jun 2022	222	203	69
Jul 2022	217	199	59
Aug 2022	229	213	56
Sep 2022	293	260	85
Oct 2022	278	250	90
Nov 2022	260	241	104
Dec 2022	263	246	85
Jan 2023	277	243	69
Feb 2023	315	271	81
Mar 2023	315	283	84
Apr 2023	242	221	70
May 2023	256	218	61
Jun 2023	249	222	52
Jul 2023	284	252	90
Aug 2023	255	220	57
Sep 2023	225	203	45
Oct 2023	243	209	57
Nov 2023	301	240	93
Dec 2023	1795	189	73
Jan 2024	163	165	114
Feb 2024	153	145	102
Mar 2024	255	235	105
Total	27357	24248	9194

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