Gut: 66 (6)

Commentaries

Putting the Wnt up colon cancer (10 November, 2016)
Lukas JAC Hawinkels, James CH Hardwick
Apicobasal polarity and Ras/Raf/MEK/ERK signalling in cancer (14 December, 2016)
Juan Peng, Ama Gassama-Diagne
Telomere length and pancreatic cancer risk: breaking down the evidence (5 December, 2016)
Eric J Duell

Guidelines

UK guideline on transition of adolescent and young persons with chronic digestive diseases from paediatric to adult care (21 February, 2017)
Alenka J Brooks, Philip J Smith, Richard Cohen, Paul Collins, Andrew Douds, Valda Forbes, Daniel R Gaya, Brian T Johnston, Patrick J McKiernan, Charles D Murray, Shaji Sebastian, Monica Smith, Lisa Whitley, Lesley Williams, Richard K Russell, Sara A McCartney, James O Lindsay

Stomach

Original article: Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis (1 March, 2016)
Gail B Gifford, Elise S Demitrack, Theresa M Keeley, Andrew Tam, Nilsa La Cunza, Priya H Dedhia, Jason R Spence, Diane M Simeone, Ichiko Saotome, Angeliki Louvi, Christian W Siebel, Linda C Samuelson
Original article:
Deletion of Men1 and somatostatin induces hypergastrinemia and gastric carcinoids
(9 February, 2016)
Sinju Sundaresan, Anthony J Kang, Michael M Hayes, Eun-Young K Choi, Juanita L Merchant

Endoscopy

Original article: The learning curve to achieve satisfactory completion rates in upper GI endoscopy: an analysis of a national training database (14 March, 2016)
S T Ward, A Hancox, M A Mohammed, T Ismail, E A Griffiths, R Valori, P Dunckley

Gut microbiota

Original article: The effect of heritability and host genetics on the gut microbiota and metabolic syndrome (6 April, 2016)
Mi Young Lim, Hyun Ju You, Hyo Shin Yoon, Bomi Kwon, Jae Yoon Lee, Sunghee Lee, Yun-Mi Song, Kayoung Lee, Joohon Sung, GwangPyo Ko

Inflammatory bowel disease

Original article: Fungal microbiota dysbiosis in IBD (3 February, 2016)
Harry Sokol, Valentin Leducq, Hugues Aschard, Hang-Phuong Pham, Sarah Jegou, Cecilia Landman, David Cohen, Giuseppina Liguori, Anne Bourrier, Isabelle Nion-Larmurier, Jacques Cosnes, Philippe Seksik, Philippe Langella, David Skurnik, Mathias L Richard, Laurent Beaugerie
Original article: Tofacitinib for induction and maintenance therapy of Crohn's disease: results of two phase IIb randomised placebo-controlled trials (16 February, 2017)
Julian Panés, William J Sandborn, Stefan Schreiber, Bruce E Sands, Séverine Vermeire, Geert D'Haens, Remo Panaccione, Peter D R Higgins, Jean-Frederic Colombel, Brian G Feagan, Gary Chan, Michele Moscariello, Wenjin Wang, Wojciech Niezychowski, Amy Marren, Paul Healey, Eric Maller
Original article: Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann–Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease (7 March, 2016)
Tobias Schwerd, Sumeet Pandey, Huei-Ting Yang, Katrin Bagola, Elisabeth Jameson, Jonathan Jung, Robin H Lachmann, Neil Shah, Smita Y Patel, Claire Booth, Heiko Runz, Gesche Düker, Ruth Bettels, Marianne Rohrbach, Subra Kugathasan, Helen Chapel, Satish Keshav, Abdul Elkadri, Nick Platt, Alexio M Muise, Sibylle Koletzko, Ramnik J Xavier, Thorsten Marquardt, Fiona Powrie, James E Wraith, Mads Gyrd-Hansen, Frances M Platt, Holm H Uhlig

Neurogastroenterology

Original article: The global prevalence of IBS in adults remains elusive due to the heterogeneity of studies: a Rome Foundation working team literature review (27 January, 2016)
Ami D Sperber, Dan Dumitrascu, Shin Fukudo, Charles Gerson, Uday C Ghoshal, Kok Ann Gwee, A Pali S Hungin, Jin-Yong Kang, Chen Minhu, Max Schmulson, Arkady Bolotin, Michael Friger, Tamar Freud, William Whitehead
Original article:
α-Conotoxin Vc1.1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABA_B receptors
(17 February, 2016)
Joel Castro, Andrea M Harrington, Sonia Garcia-Caraballo, Jessica Maddern, Luke Grundy, Jingming Zhang, Guy Page, Paul E Miller, David J Craik, David J Adams, Stuart M Brierley

GI cancer

Original article: RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis (10 August, 2016)
John Hilkens, Nikki C Timmer, Mandy Boer, Gerjon J Ikink, Matthias Schewe, Andrea Sacchetti, Martijn A J Koppens, Ji-Ying Song, Elvira R M Bakker

Colon

Original article: Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs tumour growth in human colorectal cancer (26 September, 2016)
Tijana Borovski, Thomas T Vellinga, Jamila Laoukili, Evan E Santo, Szabolcs Fatrai, Susanne van Schelven, Andre Verheem, Dieuwke L Marvin, Inge Ubink, Inne H M Borel Rinkes, Onno Kranenburg

Pancreas

Original article:
Leucocyte telomere length, genetic variants at the TERT gene region and risk of pancreatic cancer
(21 October, 2016) Free
Ying Bao, Jennifer Prescott, Chen Yuan, Mingfeng Zhang, Peter Kraft, Ana Babic, Vicente Morales-Oyarvide, Zhi Rong Qian, Julie E Buring, Barbara B Cochrane, J Michael Gaziano, Edward L Giovannucci, JoAnn E Manson, Kimmie Ng, Shuji Ogino, Thomas E Rohan, Howard D Sesso, Meir J Stampfer, Charles S Fuchs, Immaculata De Vivo, Laufey T Amundadottir, Brian M Wolpin

Hepatology

Original article: Signalling via the osteopontin and high mobility group box-1 axis drives the fibrogenic response to liver injury (27 January, 2016)
Elena Arriazu, Xiaodong Ge, Tung-Ming Leung, Fernando Magdaleno, Aritz Lopategi, Yongke Lu, Naoto Kitamura, Raquel Urtasun, Neil Theise, Daniel J Antoine, Natalia Nieto

Recent advances in clinical practice

Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases (17 March, 2017) Free
Leon A Adams, Quentin M Anstee, Herbert Tilg, Giovanni Targher
Drug-induced liver injury: recent advances in diagnosis and risk assessment (23 March, 2017)
Gerd A Kullak-Ublick, Raul J Andrade, Michael Merz, Peter End, Andreas Benesic, Alexander L Gerbes, Guruprasad P Aithal

JournalScan

GI highlights from the literature (12 May, 2017)
Mairi H McLean

PostScript

Letter: Dyspepsia and the microbiome: time to focus on the small intestine (3 August, 2016)
Laurie Zhong, Erin R Shanahan, Ashok Raj, Natasha A Koloski, Linda Fletcher, Mark Morrison, Marjorie M Walker, Nicholas J Talley, Gerald Holtmann
Letter: The γ-glutamyl transpeptidase to platelet ratio (GPR) in HBV patients: just adding up? (17 August, 2016)
Leonardo L Schiavon, Janaína L Narciso-Schiavon, Maria Lucia G Ferraz, Antonio E B Silva, Roberto J Carvalho-Filho
Letter:
Lack of evidence for germline RNF43 mutations in patients with serrated polyposis syndrome from a large multinational study
(31 August, 2016)
Daniel D Buchanan, Mark Clendenning, Li Zhuoer, Jenna R Stewart, Sharelle Joseland, Sonja Woodall, Julie Arnold, Kara Semotiuk, Melyssa Aronson, Spring Holter, Steven Gallinger, Mark A Jenkins, Kevin Sweet, Finlay A Macrae, Ingrid M Winship, Susan Parry, Christophe Rosty
Letter: Percutaneous cooled-probe microwave versus radiofrequency ablation in early-stage hepatocellular carcinoma: a phase III randomised controlled trial (24 November, 2016)
Jie Yu, Xiao-ling Yu, Zhi-yu Han, Zhi-gang Cheng, Fang-yi Liu, Hong-yan Zhai, Meng-juan Mu, Yan-mei Liu, Ping Liang
Letter: Clarifying misunderstandings and misinterpretations about proton pump inhibitor-responsive oesophageal eosinophilia (13 September, 2016)
Javier Molina-Infante, Ikuo Hirano, Stuart J Spechler

Editor’s quiz: GI snapshot

A rare cause of GI bleeding in a 56-year-old man (20 December, 2016)
Pao-Ying Lin, Jui-Hsiang Tang, Chun-Chao Chang

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Table of contents

June 2017 - Volume 66 - 6

Commentaries

Guidelines

Stomach

Endoscopy

Gut microbiota

Inflammatory bowel disease

Neurogastroenterology

GI cancer

Colon

Pancreas

Hepatology

Recent advances in clinical practice

JournalScan

PostScript

Editor’s quiz: GI snapshot

Issue Information

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Table of contents

June 2017 - Volume 66 - 6

Commentaries

Guidelines

Stomach

Endoscopy

Gut microbiota

Inflammatory bowel disease

Neurogastroenterology

GI cancer

Colon

Pancreas

Hepatology

Recent advances in clinical practice

JournalScan

PostScript

Editor’s quiz: GI snapshot

Issue Information