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We thank Gut for requesting responses to this letter from Oberhuber and colleagues.1 We were amazed that they chose to dismiss our intraepithelial lymphocytes (IEL) data as invalid2 on grounds of not being age/gender matched with controls. But this disregards all the other data of clinicians and pathologists in the field, and the rigorous reviewing processes that our article went through before publication in Gut. This dismissal reflects an aberrant viewpoint1 lacking widespread support. In real life, pathologists do sign off biopsies, while diagnoses are rendered without full clinical details, although with appropriately worded caveats.
We aimed, specifically, to reduce the enormous …
Contributors KR, AE, CC, AS, UV, VV and MNM have written their responses, and the final version of the letter based on the written responses and email discussion was summarized and formulated by MNM. The discussion was coordinated by KR. The authors have revised and agreed on the final version of the manuscript after several revisions.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.