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We read with interest the work by Cheung et al 1 describing that patients with prior Helicobacter pylori eradication therapy receiving long-term proton pump inhibitors (PPIs) therapy are still at enhanced risk of gastric cancer development, particularly for non-cardia cancer. As the current consensus report stated, long-term treatment with PPIs in H. pylori-positive patients accelerates the process of loss of specialised glands, leading to atrophic gastritis. Hence, it is recommended that eradication of H. pylori heals gastritis in patients …
Contributors Written by C-BZ. Revised by J-YF.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.
Correction notice This article has been corrected since it published Online First. The order of the authors has been corrected.
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