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A 53-year-old man was admitted with a 2-week history of bowel obstruction on a background of gradually worsening dyspeptic symptoms associated with vomiting and weight loss. He was under regular gastroenterology review for Barrett’s oesophagus and had a recent endoscopic diagnosis of megaduodenum (mainly D1 dilatation) confirmed by barium study (figure 1). He was also known to have bladder emptying problems and an enlarged bladder. His mother died at age 28 due to ‘megacolon’, and he has a monozygotic twin brother with Barrett’s oesophagus.
Contributors CHK and AL conceived the study. AL wrote the manuscript. TFJC and AA collected and edited the data. JEM analysed the data. CHK and JEM critically revised the manuscript.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.