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Original article
The active bacterial assemblages of the upper GI tract in individuals with and without Helicobacter infection
  1. Christian Schulz1,2,
  2. Kerstin Schütte1,3,
  3. Nadine Koch2,
  4. Ramiro Vilchez-Vargas1,
  5. Melissa L Wos-Oxley2,
  6. Andrew P A Oxley2,4,
  7. Marius Vital2,
  8. Peter Malfertheiner1,
  9. Dietmar H Pieper2
  1. 1 Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany
  2. 2 Microbial Interactions and Processes (MINP) Research Group, Helmholtz Centre for Infection Research, Braunschweig, Germany
  3. 3 Department of Internal Medicine and Gastroenterology, Niels-Stensen-Kliniken, Marienhospital, Osnabrück, Germany
  4. 4 Molecular Sciences Laboratory, SARDI Aquatic Sciences, West Beach, South Australia, Australia
  1. Correspondence to Professor Dietmar H Pieper, Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstraße 7, Braunschweig 38124, Germany; dpi{at}helmholtz-hzi.de

Footnotes

  • Contributors DHP, PM and CS contributed to the study design, analysis and interpretation of the data. DHP and CS drafted the manuscript. CS, KS and PM collected samples and identified suitable subjects. DHP and PM supervised the study procedures. CS, NK and APAO established analyses and performed laboratory workup. MV, DHP, MLW-O and RV-V performed bioinformatic and statistical analyses. All authors read and approved the final version of the manuscript.

  • Funding This study was supported by iMed, the Helmholtz Association's Initiative on Personalized Medicine. CS was supported by CRC854, a research programme by the German funding organisation DFG.

  • Competing interests None.

  • Ethics approval University of Magdeburg operation number 31/11.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • Contributors DHP, PM and CS contributed to the study design, analysis and interpretation of the data. DHP and CS drafted the manuscript. CS, KS and PM collected samples and identified suitable subjects. DHP and PM supervised the study procedures. CS, NK and APAO established analyses and performed laboratory workup. MV, DHP, MLW-O and RV-V performed bioinformatic and statistical analyses. All authors read and approved the final version of the manuscript.

  • Funding This study was supported by iMed, the Helmholtz Association's Initiative on Personalized Medicine. CS was supported by CRC854, a research programme by the German funding organisation DFG.

  • Competing interests None.

  • Ethics approval University of Magdeburg operation number 31/11.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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