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Contributors Study was designed and clinical participants were recruited by GLR-S. Assay and technical expertise provided by RS. Data were collected by PH. Control participants were recruited by KH. Analysis was performed by ARL and LAS. Manuscript was written by ARL, LAS and GLR-S. Figures were created by ARL. Manuscript was reviewed by all authors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.