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Hepatology
Original article
The HLF/IL-6/STAT3 feedforward circuit drives hepatic stellate cell activation to promote liver fibrosis

Authors

  • Dai-Min Xiang The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China Nelson Institute of Environmental Medicine, New York University School of Medicine, New York, USA National Center for Liver Cancer, Shanghai, China PubMed articlesGoogle scholar articles
  • Wen Sun The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Bei-Fang Ning Department of Gastroenterology, Changzheng Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Teng-Fei Zhou The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Xiao-Feng Li The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Wei Zhong Department of Gastroenterology, Renji Hospital, Shanghai Jiaotong University, Shanghai, China PubMed articlesGoogle scholar articles
  • Zhuo Cheng The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Ming-Yang Xia The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Xue Wang The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Xing Deng Department of Gastroenterology, Changzheng Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Wei Wang Department of Gastroenterology, Changzheng Hospital, Second Military Medical University, Shanghai, China Department of Gastroenterology, Lanzhou General Hospital of Lanzhou Military Command, Lanzhou, China PubMed articlesGoogle scholar articles
  • Heng-Yu Li The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Xiu-Liang Cui The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Shi-Chao Li The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Bin Wu Department of Gastroenterology and Endoscopy, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China PubMed articlesGoogle scholar articles
  • Wei-Fen Xie Department of Gastroenterology, Changzheng Hospital, Second Military Medical University, Shanghai, China PubMed articlesGoogle scholar articles
  • Hong-Yang Wang The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China National Center for Liver Cancer, Shanghai, China PubMed articlesGoogle scholar articles
  • Jin Ding The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China National Center for Liver Cancer, Shanghai, China PubMed articlesGoogle scholar articles
  1. Correspondence to Hong-Yang Wang and Jin Ding, The International Cooperation Laboratory on Signal Transduction, Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, 225 Changhai Road, 200438 Shanghai, China; hywangk{at}vip.sina.com, dingjin1103{at}163.com
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Citation

Xiang D, Sun W, Ning B, et al
The HLF/IL-6/STAT3 feedforward circuit drives hepatic stellate cell activation to promote liver fibrosis
Gut 2018;67:1704-1715.

Publication history

  • Received November 14, 2016
  • Revised June 7, 2017
  • Accepted June 11, 2017
  • First published July 28, 2017.
Online issue publication 
August 13, 2018

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