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Original article
SRSF6-regulated alternative splicing that promotes tumour progression offers a therapy target for colorectal cancer
  1. Ledong Wan1,
  2. Wenying Yu2,
  3. Enhui Shen3,
  4. Wenjie Sun1,
  5. Yuan Liu1,
  6. Jianlu Kong1,
  7. Yihua Wu4,
  8. Fengyan Han1,
  9. Lei Zhang1,5,
  10. Tianze Yu1,
  11. Yuwei Zhou1,
  12. Sunzhe Xie1,
  13. Enping Xu1,
  14. Honghe Zhang1,
  15. Maode Lai1,5
  1. 1 Department of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, School of Medicine, Zhejiang University, Hangzhou, China
  2. 2 State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China
  3. 3 College of Agriculture and Biotechnology, Institute of Bioinformatics, Zhejiang University, Hangzhou, China
  4. 4 Department of Toxicology, School of Public Health, Zhejiang University, Hangzhou, Zhejiang, China
  5. 5 Department of Pharmacology, China Pharmaceutical University, Nanjing, China
  1. Correspondence to Dr Honghe Zhang and Prof. Maode Lai, Department of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, School of Medicine, Zhejiang University, Hangzhou 310058, China; honghezhang{at}zju.edu.cn, lmp{at}zju.edu.cn

Footnotes

  • Contributors Conceptualisation: HZ and ML; methodology: LW, WY, ES and WS; investigation: LW, YL, JK, FH, LZ, TY, YZ and SX; resources: WY, ES, WS, YW and EX; writing-original draft: HZ and LW; writing-review and editing: HZ and ML; supervision: HZ and ML; funding acquisition: HZ and ML.

  • Funding This work is supported by grants from the National Natural Science Foundation of China (81672730 to HZ and 81572716 to ML), the 111 Project (B13026 to ML) and the Fundamental Research Funds for the Central Universities (172210271 to HZ).

  • Competing interests None declared.

  • Ethics approval The protocols (2015027) were approved by the Review Board of Zhejiang University.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • Contributors Conceptualisation: HZ and ML; methodology: LW, WY, ES and WS; investigation: LW, YL, JK, FH, LZ, TY, YZ and SX; resources: WY, ES, WS, YW and EX; writing-original draft: HZ and LW; writing-review and editing: HZ and ML; supervision: HZ and ML; funding acquisition: HZ and ML.

  • Funding This work is supported by grants from the National Natural Science Foundation of China (81672730 to HZ and 81572716 to ML), the 111 Project (B13026 to ML) and the Fundamental Research Funds for the Central Universities (172210271 to HZ).

  • Competing interests None declared.

  • Ethics approval The protocols (2015027) were approved by the Review Board of Zhejiang University.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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