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Original article
Single-cell RNAseq reveals seven classes of colonic sensory neuron
  1. James R F Hockley1,2,
  2. Toni S Taylor1,
  3. Gerard Callejo1,
  4. Anna L Wilbrey2,
  5. Alex Gutteridge2,
  6. Karsten Bach1,
  7. Wendy J Winchester2,
  8. David C Bulmer1,
  9. Gordon McMurray2,
  10. Ewan St John Smith1
  1. 1 Department of Pharmacology, University of Cambridge, Cambridge, UK
  2. 2 Neuroscience and Pain Research Unit, Pfizer, Cambridge, UK
  1. Correspondence to James R F Hockley, Department of Pharmacology, University of Cambridge, Cambridge, UK; jh2033{at}cam.ac.uk and Dr Ewan St John Smith, Department of Pharmacology, University of Cambridge, Cambridge CB1 2PD, UK; es336{at}cam.ac.uk

Footnotes

  • Contributors JRFH, DCB, WJW and EStJS designed the study. JRFH, TST, GC and ALW undertook experiments. JRFH, TST, AG, KB, DCB and GM analysed the data. JRFH, DCB and EStJS wrote the manuscript in conjunction with all other authors.

  • Funding This work was supported by Neusentis (Pfizer) in the form of salaries for authors (JRFH, ALW, AG, WJW and GM), but did not have any additional role in the study design, data collection and analysis, decision to publish or preparation of the manuscript. Additionally, this work is supported by a Rosetrees Postdoctoral Grant (A1296) awarded to JRFH and EStJS, Medical Research Council Grant (G0900907) to DCB, University of Cambridge Vice Chancellor’s Award (TST), Arthritis Research UK Grant to GC and EStJS (RG 20930). KB is funded by a Cambridge Cancer Centre studentship.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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Footnotes

  • Contributors JRFH, DCB, WJW and EStJS designed the study. JRFH, TST, GC and ALW undertook experiments. JRFH, TST, AG, KB, DCB and GM analysed the data. JRFH, DCB and EStJS wrote the manuscript in conjunction with all other authors.

  • Funding This work was supported by Neusentis (Pfizer) in the form of salaries for authors (JRFH, ALW, AG, WJW and GM), but did not have any additional role in the study design, data collection and analysis, decision to publish or preparation of the manuscript. Additionally, this work is supported by a Rosetrees Postdoctoral Grant (A1296) awarded to JRFH and EStJS, Medical Research Council Grant (G0900907) to DCB, University of Cambridge Vice Chancellor’s Award (TST), Arthritis Research UK Grant to GC and EStJS (RG 20930). KB is funded by a Cambridge Cancer Centre studentship.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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