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HBV antiviral immunity: not all CD8 T cells are born equal

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  • Contributors Both authors contributed to the writing of this commentary.

  • Funding This work was supported by a Singapore Translational Research (STaR) investigator award (NMRC/STaR/Nov 004/2018) of National Medical Research Council of Singapore to AB and a Barts and The London Charity Large Project grant (723/1795) to PTFK.

  • Competing interests AB receives research support from Gilead Sciences to test the effect of HBV antigens on immune cell function. He acted as a consultant and served on the advisory boards of Gilead Sciences, Janssen-Cilag, Vir, HUMABS BioMed, SpringBank and Jiangsu Simcere Pharmaceutical. He is also a cofounder of Lion TCR, a biotech company developing T-cell receptors for treatment of virus-related cancers. PTFK has collaborative grant funding from Gilead Sciences, participates in advisory board/provides consultancy to Gilead Sciences and Janssen, and is an investigator for industry-led trials with Gilead Sciences, Janssen, Alere and Assembly Biosciences.

  • Provenance and peer review Commissioned; internally peer reviewed.

  • Patient consent for publication Not required.

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