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Contributors FJC and MLM-C contributed equally in the writing of the commentary.
Funding FJC was supported by the MINECO Retos SAF2016-78711, EXOHEP-CM S2017/BMD-3727, NanoLiver-CM Y2018/NMT-4949, ERAB Ref. EA 18/14, AMMF 2018/117 and COST Action CA17112. FJC is a Ramón y Cajal Researcher (RYC-2014-15242) and a Gilead Liver Research Scholar. MLM-C was supported by grants from NIH (US Department of Health and Human Services)-R01AR001576-11A1, Gobierno Vasco-Departamento de Salud 2013111114, ELKARTEK 2016, Departamento de Industria del Gobierno Vasco, MINECO: SAF2017–87301-R integrado en el Plan Estatal de Investigación Científica y Técnica y Innovación 2013–2016 cofinanciado con Fondos FEDER, BIOEF (Basque Foundation for Innovation and Health Research): EITB Maratoia BIO15/CA/014; Instituto de Salud Carlos III:PIE14/00031, integrado en el Plan Estatal de Investigación Científica y Técnica y Innovación 2013–2016 cofinanciado con Fondos FEDER and the Asociación Española contra el Cáncer. The CIC bioGUNE is a Severo Ochoa Excellence Accreditation Center (SEV-2016-0644).
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.
Patient consent for publication Not required.