Gut: 69 (1)

Commentaries

Targeting tumour microenvironment, a FAKtual challenge in pancreatic cancer (3 October, 2019)
Ezequiel J Tolosa, Martín E Fernández-Zapico
Life is fragile: FMRP controls cell death in liver disease (25 September, 2019) Free
Mihael Vucur, Tom Luedde

Endoscopy news

Deep-learning based detection of gastric precancerous conditions (2 August, 2019) Free
Pedro Guimarães, Andreas Keller, Tobias Fehlmann, Frank Lammert, Markus Casper

Guidelines

Management of patients with increased risk for familial pancreatic cancer: updated recommendations from the International Cancer of the Pancreas Screening (CAPS) Consortium (31 October, 2019) Free
Michael Goggins, Kasper Alexander Overbeek, Randall Brand, Sapna Syngal, Marco Del Chiaro, Detlef K Bartsch, Claudio Bassi, Alfredo Carrato, James Farrell, Elliot K Fishman, Paul Fockens, Thomas M Gress, Jeanin E van Hooft, R H Hruban, Fay Kastrinos, Allison Klein, Anne Marie Lennon, Aimee Lucas, Walter Park, Anil Rustgi, Diane Simeone, Elena Stoffel, Hans F A Vasen, Djuna L Cahen, Marcia Irene Canto, Marco Bruno

Stomach

Original article: Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response (6 June, 2019)
Ruiping Wang, Shumei Song, Kazuto Harada, Fatemeh Ghazanfari Amlashi, Brian Badgwell, Melissa Pool Pizzi, Yan Xu, Wei Zhao, Xiaochuan Dong, Jiangkang Jin, Ying Wang, Ailing Scott, Lang Ma, Longfei Huo, Diego Vicente, Mariela Blum Murphy, Namita Shanbhag, Ghia Tatlonghari, Irene Thomas, Jane Rogers, Makoto Kobayashi, Jody Vykoukal, Jeannelyn Santiano Estrella, Sinchita Roy-Chowdhuri, Guangchun Han, Shaojun Zhang, Xizeng Mao, Xingzhi Song, Jianhua Zhang, Jian Gu, Randy L Johnson, George Adrian Calin, Guang Peng, Ju-Seog Lee, Samir M Hanash, Andrew Futreal, Zhenning Wang, Linghua Wang, Jaffer A Ajani

Inflammatory bowel disease

Original article: Designing clinical trials in paediatric inflammatory bowel diseases: a PIBDnet commentary (12 April, 2019) Free
Dan Turner, Anne M Griffiths, David Wilson, Diane R Mould, Robert N Baldassano, Richard K Russell, Marla Dubinsky, Melvin B Heyman, Lissy de Ridder, Jeffrey Hyams, Javier Martin de Carpi, Laurie Conklin, William A Faubion, Sibylle Koletzko, Athos Bousvaros, Frank M Ruemmele
Original article: Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice (29 April, 2019) Free
Joana Torres, Jianzhong Hu, Akihiro Seki, Caroline Eisele, Nilendra Nair, Ruiqi Huang, Leonid Tarassishin, Bindia Jharap, Justin Cote-Daigneault, Qixing Mao, Ilaria Mogno, Graham J Britton, Mathieu Uzzan, Ching-Lynn Chen, Asher Kornbluth, James George, Peter Legnani, Elana Maser, Holly Loudon, Joanne Stone, Marla Dubinsky, Jeremiah J Faith, Jose C Clemente, Saurabh Mehandru, Jean-Frederic Colombel, Inga Peter

Endoscopy

Original article: Integrating next-generation sequencing to endoscopic retrograde cholangiopancreatography (ERCP)-obtained biliary specimens improves the detection and management of patients with malignant bile duct strictures (10 April, 2019)
Aatur D Singhi, Marina N Nikiforova, Jennifer Chennat, Georgios I Papachristou, Asif Khalid, Mordechai Rabinovitz, Rohit Das, Savreet Sarkaria, M Samir Ayasso, Abigail I Wald, Sara E Monaco, Michael Nalesnik, N Paul Ohori, David Geller, Allan Tsung, Amer H Zureikat, Herbert Zeh, J Wallis Marsh, Melissa Hogg, Kenneth Lee, David L Bartlett, James F Pingpank, Abhinav Humar, Nathan Bahary, Anil K Dasyam, Randall Brand, Kenneth E Fasanella, Kevin McGrath, Adam Slivka

Neurogastroenterology

Original article: Serine proteases as luminal mediators of intestinal barrier dysfunction and symptom severity in IBS (28 March, 2019) Free
Shoko Edogawa, Adam L Edwinson, Stephanie A Peters, Lakshmikanth L Chikkamenahalli, Wendy Sundt, Sara Graves, Sakteesh V Gurunathan, Margaret Breen-Lyles, Stephen Johnson, Roy Dyer, Rondell Graham, Jun Chen, Purna Kashyap, Gianrico Farrugia, Madhusudan Grover
Original article: Efficacy of pharmacological therapies in patients with IBS with diarrhoea or mixed stool pattern: systematic review and network meta-analysis (17 April, 2019) Free
Christopher J Black, Nicholas E Burr, Michael Camilleri, David L Earnest, Eamonn MM Quigley, Paul Moayyedi, Lesley A Houghton, Alexander C Ford

Gut microbiota

Original article: Scientific frontiers in faecal microbiota transplantation: joint document of Asia-Pacific Association of Gastroenterology (APAGE) and Asia-Pacific Society for Digestive Endoscopy (APSDE) (14 October, 2019)
Siew C Ng, Michael A Kamm, Yun Kit Yeoh, Paul K S Chan, Tao Zuo, Whitney Tang, Ajit Sood, Akira Andoh, Naoki Ohmiya, Yongjian Zhou, Choon Jin Ooi, Varocha Mahachai, Chun-Ying Wu, Faming Zhang, Kentaro Sugano, Francis K L Chan
Original article: Fungi participate in the dysbiosis of gut microbiota in patients with primary sclerosing cholangitis (19 April, 2019) Free
Sara Lemoinne, Astrid Kemgang, Karima Ben Belkacem, Marjolène Straube, Sarah Jegou, Christophe Corpechot, Saint-Antoine IBD Network, Olivier Chazouillères, Chantal Housset, Harry Sokol

Colon

Original article: Low plasma vitamin D is associated with adverse colorectal cancer survival after surgical resection, independent of systemic inflammatory response (25 April, 2019)
P G Vaughan-Shaw, L Zgaga, L Y Ooi, E Theodoratou, M Timofeeva, V Svinti, M Walker, F O’Sullivan, A Ewing, S Johnston, F V N Din, H Campbell, S M Farrington, M G Dunlop
Original article: Personalised surveillance for serrated polyposis syndrome: results from a prospective 5-year international cohort study (13 April, 2019)
Arne GC Bleijenberg, Joep EG IJspeert, Yasmijn J van Herwaarden, Sabela Carballal, María Pellisé, Gerhard Jung, Tanya M Bisseling, Iris D Nagetaal, Monique E van Leerdam, Niels van Lelyveld, Xavier Bessa, Francisco Rodríguez-Moranta, Barbara Bastiaansen, Willemijn de Klaver, Liseth Rivero, Manon CW Spaander, Jan Jacob Koornstra, Luis Bujanda, Francesc Balaguer, Evelien Dekker

Pancreas

Original article: Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion (10 May, 2019) Free
Hong Jiang, Xiuting Liu, Brett L Knolhoff, Samarth Hegde, Kyung Bae Lee, Hongmei Jiang, Ryan C Fields, Jonathan A Pachter, Kian-Huat Lim, David G DeNardo

Hepatology

Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury (13 August, 2019)
Yuan Zhuang, Haifeng C Xu, Prashant V Shinde, Jens Warfsmann, Jelena Vasilevska, Balamurugan Sundaram, Kristina Behnke, Jun Huang, Jessica I Hoell, Arndt Borkhardt, Klaus Pfeffer, Mohamed S Taha, Diran Herebian, Ertan Mayatepek, Dirk Brenner, Mohammad Reza Ahmadian, Verena Keitel, Dagmar Wieczorek, Dieter Häussinger, Aleksandra A Pandyra, Karl S Lang, Philipp A Lang
Original article: TGR5-dependent hepatoprotection through the regulation of biliary epithelium barrier function (5 February, 2019) Free
Grégory Merlen, Nicolas Kahale, Jose Ursic-Bedoya, Valeska Bidault-Jourdainne, Hayat Simerabet, Isabelle Doignon, Zahra Tanfin, Isabelle Garcin, Noémie Péan, Julien Gautherot, Anne Davit-Spraul, Catherine Guettier, Lydie Humbert, Dominique Rainteau, Klaus Ebnet, Christoph Ullmer, Doris Cassio, Thierry Tordjmann
Original Article: Combined small molecule and loss-of-function screen uncovers estrogen receptor alpha and CAD as host factors for HDV infection and antiviral targets (4 March, 2019)
Eloi R Verrier, Amélie Weiss, Charlotte Bach, Laura Heydmann, Vincent Turon-Lagot, Arnaud Kopp, Houssein El Saghire, Emilie Crouchet, Patrick Pessaux, Thomas Garcia, Patrick Pale, Mirjam B Zeisel, Camille Sureau, Catherine Schuster, Laurent Brino, Thomas F Baumert
Original article: Age independent survival benefit for patients with hepatocellular carcinoma (HCC) without metastases at diagnosis: a population-based study (16 March, 2019)
Enrico N De Toni, Anne Schlesinger-Raab, Martin Fuchs, Wolfgang Schepp, Ursula Ehmer, Fabian Geisler, Jens Ricke, Philipp Paprottka, Helmut Friess, Jens Werner, Alexander L Gerbes, Julia Mayerle, Jutta Engel
Original article: Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans (6 April, 2019)
Li Che, Wenna Chi, Yu Qiao, Jie Zhang, Xinhua Song, Ye Liu, Lei Li, Jiaoyuan Jia, Maria G Pilo, Jingxiao Wang, Antonio Cigliano, Zhilong Ma, Wenhua Kuang, Zefang Tang, Zemin Zhang, Guanghou Shui, Silvia Ribback, Frank Dombrowski, Matthias Evert, Rosa Maria Pascale, Carla Cossu, Giovanni Mario Pes, Timothy F Osborne, Diego F Calvisi, Xin Chen, Ligong Chen

JournalScan

GI highlights from the literature (6 December, 2019) Free
Mairi H McLean

PostScript

Letter: Animal protein intake and hepatic steatosis in the elderly: authors' response (21 November, 2018) Free
Louise Johanna Maria Alferink, Jessica Christina Kiefte-de Jong, Sarwa Darwish Murad
Letter: Authors reply: treatment strategy for necrotising pancreatitis (17 November, 2018) Free
Ji Young Bang, Shyam Varadarajulu
Letter: Role of endoscopy in chronic diarrhoea when functional bowel disease is suspected (3 December, 2018)
Ramesh P Arasaradnam, Julian R F Walters
Letter: Increased levels of systemic LPS-positive bacterial extracellular vesicles in patients with intestinal barrier dysfunction (5 December, 2018)
Joeri Tulkens, Glenn Vergauwen, Jan Van Deun, Edward Geeurickx, Bert Dhondt, Lien Lippens, Marie-Angélique De Scheerder, Ilkka Miinalainen, Pekka Rappu, Bruno G De Geest, Katrien Vandecasteele, Debby Laukens, Linos Vandekerckhove, Hannelore Denys, Jo Vandesompele, Olivier De Wever, An Hendrix
Letter: Older patients with IBD might have higher risk of Parkinson’s disease (5 December, 2018) Free
Qian-Yi Wan, Rui Zhao, Xiao-Ting Wu

Editor’s quiz: GI snapshot

Jejunal perforation and central retinal vein occlusion in a 55-year-old European man (26 April, 2019) Free
Amanda Louise Thomas, Luke Summers, James R Goodhand, Sarah Saunders

Electronic page

Correction: Expression of the type 3 InsP₃ receptor is a final common event in the development of hepatocellular carcinoma
(6 December, 2019) Free

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Table of contents

January 2020 - Volume 69 - 1

Commentaries

Endoscopy news

Guidelines

Stomach

Inflammatory bowel disease

Endoscopy

Neurogastroenterology

Gut microbiota

Colon

Pancreas

Hepatology

JournalScan

PostScript

Editor’s quiz: GI snapshot

Electronic page

Issue Information

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Table of contents

January 2020 - Volume 69 - 1

Commentaries

Endoscopy news

Guidelines

Stomach

Inflammatory bowel disease

Endoscopy

Neurogastroenterology

Gut microbiota

Colon

Pancreas

Hepatology

JournalScan

PostScript

Editor’s quiz: GI snapshot

Electronic page

Issue Information