Gut: 69 (2)

Commentary

Of FACT complex and oxidative stress response: a KEAP1/NRF2-dependent novel mechanism sustaining hepatocellular carcinoma progression (15 October, 2019)
Beatrice Foglia, Maurizio Parola

Endoscopy news

The hidden cost of colonoscopy including cost of reprocessing and infection rate: the implications for disposable colonoscopes (14 August, 2019)
Sara Larsen, Anthony Kalloo, Susan Hutfless

Guidelines

British Society of Gastroenterology/Association of Coloproctology of Great Britain and Ireland/Public Health England post-polypectomy and post-colorectal cancer resection surveillance guidelines (27 November, 2019)
Matthew D Rutter, James East, Colin J Rees, Neil Cripps, James Docherty, Sunil Dolwani, Philip V Kaye, Kevin J Monahan, Marco R Novelli, Andrew Plumb, Brian P Saunders, Siwan Thomas-Gibson, Damian J M Tolan, Sophie Whyte, Stewart Bonnington, Alison Scope, Ruth Wong, Barbara Hibbert, John Marsh, Billie Moores, Amanda Cross, Linda Sharp

Oesophagus

Phase III, randomised, double-blind, multicentre study to evaluate the efficacy and safety of vonoprazan compared with lansoprazole in Asian patients with erosive oesophagitis (13 August, 2019)
Yinglian Xiao, Shutian Zhang, Ning Dai, Guijun Fei, Khean-Lee Goh, Hoon Jai Chun, Bor-Shyang Sheu, Chui Fung Chong, Nobuo Funao, Wen Zhou, Minhu Chen

Stomach

Original research:
HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer
(8 May, 2019)
Chang Xu, Wen Fong Ooi, Aditi Qamra, Jing Tan, Benjamin Yan-Jiang Chua, Shamaine Wei Ting Ho, Kakoli Das, Zul Fazreen Adam Isa, Zhimei Li, Xiaosai Yao, Tingdong Yan, Manjie Xing, Kie Kyon Huang, Joyce Suling Lin, Tannistha Nandi, Su Ting Tay, Ming Hui Lee, Angie Lay Keng Tan, Xuewen Ong, Hassan Ashktorab, Duane Smoot, Shang Li, Shyh-Chang Ng, Bin Tean Teh, Patrick Tan

Upper GI cancer

Original research: Cancer cell niche factors secreted from cancer-associated fibroblast by loss of H3K27me3 (13 May, 2019)
Masahiro Maeda, Hideyuki Takeshima, Naoko Iida, Naoko Hattori, Satoshi Yamashita, Hiroshi Moro, Yoshimi Yasukawa, Kazuhiro Nishiyama, Taiki Hashimoto, Shigeki Sekine, Genichiro Ishii, Atsushi Ochiai, Takeo Fukagawa, Hitoshi Katai, Yoshiharu Sakai, Toshikazu Ushijima

Inflammatory bowel disease

Original research: Non-classical monocyte homing to the gut via α4β7 integrin mediates macrophage-dependent intestinal wound healing (15 May, 2019)
Lena Schleier, Maximilian Wiendl, Karin Heidbreder, Marie-Theres Binder, Raja Atreya, Timo Rath, Emily Becker, Anja Schulz-Kuhnt, Annette Stahl, Lisa Lou Schulze, Karen Ullrich, Simon F Merz, Lea Bornemann, Matthias Gunzer, Alastair J M Watson, Clemens Neufert, Imke Atreya, Markus F Neurath, Sebastian Zundler
Original research: IL23 induces IL23R recycling and amplifies innate receptor-induced signalling and cytokines in human macrophages, and the IBD-protective IL23R R381Q variant modulates these outcomes (16 May, 2019)
Rui Sun, Matija Hedl, Clara Abraham
Original research: Introduction of anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases: a population-based interrupted time series study (12 June, 2019)
Sanjay K Murthy, Jahanara Begum, Eric I Benchimol, Charles N Bernstein, Gilaad G Kaplan, Jeffrey D McCurdy, Harminder Singh, Laura Targownik, Monica Taljaard

Gut microbiota

Transfer of a healthy microbiota reduces amyloid and tau pathology in an Alzheimer’s disease animal model (30 August, 2019)
Min-Soo Kim, Yoonhee Kim, Hyunjung Choi, Woojin Kim, Sumyung Park, Dongjoon Lee, Dong Kyu Kim, Haeng Jun Kim, Hayoung Choi, Dong-Wook Hyun, June-Young Lee, Eun Young Choi, Dong-Sup Lee, Jin-Woo Bae, Inhee Mook-Jung

Endoscopy

Original research: Endoscopic duodenal mucosal resurfacing for the treatment of type 2 diabetes mellitus: one year results from the first international, open-label, prospective, multicentre study (22 July, 2019)
Annieke C G van Baar, Frits Holleman, Laurent Crenier, Rehan Haidry, Cormac Magee, David Hopkins, Leonardo Rodriguez Grunert, Manoel Galvao Neto, Paulina Vignolo, Bu’Hussain Hayee, Ann Mertens, Raf Bisschops, Jan Tijssen, Max Nieuwdorp, Caterina Guidone, Guido Costamagna, Jacques Devière, Jacques J G H M Bergman

Colon

Original research: Prospective colonoscopic study to investigate risk of colorectal neoplasms in first-degree relatives of patients with non-advanced adenomas (26 April, 2019)
Siew C Ng, Moe Htet Kyaw, Bing Yee Suen, Yee Kit Tse, Martin C S Wong, Aric J Hui, Hui Yee Tak, James Y W Lau, Joseph J Y Sung, Francis K L Chan
Original research: Synthetic indicator of the impact of colorectal cancer screening programmes on incidence rates (30 April, 2019)
Manuel Zorzi, Marco Zappa

Pancreas

Original research: Morphological classification of pancreatic ductal adenocarcinoma that predicts molecular subtypes and correlates with clinical outcome (14 June, 2019)
Sangeetha N Kalimuthu, Gavin W Wilson, Robert C Grant, Matthew Seto, Grainne O’Kane, Rajkumar Vajpeyi, Faiyaz Notta, Steven Gallinger, Runjan Chetty

Hepatology

Histone chaperone FACT complex mediates oxidative stress response to promote liver cancer progression (22 August, 2019)
Jialing Shen, Mengnuo Chen, Derek Lee, Cheuk-Ting Law, Lai Wei, Felice Ho-Ching Tsang, Don Wai-Ching Chin, Carol Lai-Hung Cheng, Joyce Man-Fong Lee, Irene Oi-Lin Ng, Carmen Chak-Lui Wong, Chun-Ming Wong
Original research: A unique B cell epitope-based particulate vaccine shows effective suppression of hepatitis B surface antigen in mice (29 March, 2019)
Tian-Ying Zhang, Xue-Ran Guo, Yang-Tao Wu, Xiao-Zhen Kang, Qing-Bing Zheng, Ruo-Yao Qi, Bin-Bing Chen, Ying Lan, Min Wei, Shao-Juan Wang, Hua-Long Xiong, Jia-Li Cao, Bao-Hui Zhang, Xiao-Yang Qiao, Xiao-Fen Huang, Ying-Bin Wang, Mu-Jin Fang, Ya-Li Zhang, Tong Cheng, Yi-Xin Chen, Qin-Jian Zhao, Shao-Wei Li, Sheng-Xiang Ge, Pei-Jer Chen, Jun Zhang, Quan Yuan, Ning-shao Xia
Original research: Polyploidy spectrum: a new marker in HCC classification (12 April, 2019)
Myriam Bou-Nader, Stefano Caruso, Romain Donne, Séverine Celton-Morizur, Julien Calderaro, Géraldine Gentric, Mathilde Cadoux, Antoine L’Hermitte, Christophe Klein, Thomas Guilbert, Miguel Albuquerque, Gabrielle Couchy, Valérie Paradis, Jean-Pierre Couty, Jessica Zucman-Rossi, Chantal Desdouets
Original research: Targeting monocyte-intrinsic enhancer reprogramming improves immunotherapy efficacy in hepatocellular carcinoma (10 May, 2019)
Man Liu, Jingying Zhou, Xiaoyu Liu, Yu Feng, Weiqin Yang, Feng Wu, Otto Ka-Wing Cheung, Hanyong Sun, Xuezhen Zeng, Wenshu Tang, Myth T S Mok, John Wong, Philip Chun Yeung, Paul Bo San Lai, Zhiwei Chen, Hongchuan Jin, Jie Chen, Stephen Lam Chan, Anthony W H Chan, Ka Fai To, Joseph J Y Sung, Minhu Chen, Alfred Sze-Lok Cheng
Original research: Functional microRNA screen uncovers O-linked N-acetylglucosamine transferase as a host factor modulating hepatitis C virus morphogenesis and infectivity (10 May, 2019)
Katharina Herzog, Simonetta Bandiera, Sophie Pernot, Catherine Fauvelle, Frank Jühling, Amélie Weiss, Anne Bull, Sarah C Durand, Béatrice Chane-Woon-Ming, Sébastien Pfeffer, Marion Mercey, Hervé Lerat, Jean-Christophe Meunier, Wolfgang Raffelsberger, Laurent Brino, Thomas F Baumert, Mirjam B Zeisel

JournalScan

GI highlights from the literature (7 January, 2020)
Mairi H McLean

PostScript

Letter: Hepatitis D prevalence: problems with extrapolation to global population estimates (19 December, 2018)
Alexander J Stockdale, Benno Kreuels, Marc R Y Henrion, Emanuele Giorgi, Irene Kyomuhangi, Anna Maria Geretti
Letter:
Reduced efficacy of low FODMAPs diet in patients with IBS-D carrying sucrase-isomaltase (SI) hypomorphic variants
(18 January, 2019)
Tenghao Zheng, Shanti Eswaran, Amanda L Photenhauer, Juanita L Merchant, William D Chey, Mauro D’Amato
Letter:
Follow-on rifaximin for the prevention of recurrence following standard treatment of infection with Clostridium difficile: a competing risks analysis provides a full picture of possible treatment effects
(28 December, 2018)
Maja Katharina von Cube, Martin Schumacher, Martin Wolkewitz
Letter: Identification of trimethylamine N-oxide (TMAO)-producer phenotype is interesting, but is it helpful? (11 January, 2019)
Arduino Arduini, Victor A Zammit, Mario Bonomini
Letter: Microscopic heterogeneity in ulcerative colitis: implications for microscopic measurement of disease activity (5 February, 2019)
Noam Harpaz, Samuel Ballentine, Jean-Frederic Colombel, Bruce E Sands, Huabin Mabel Ko

Editor’s quiz: GI snapshot

Biliary dilatation in a 67-year-old woman: seeing is believing (17 April, 2019)
Peng Pan, Sheng-bing Zhao, Shuling Wang, Zhaoshen Li, Yu Bai

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Table of contents

February 2020 - Volume 69 - 2

Commentary

Endoscopy news

Guidelines

Oesophagus

Stomach

Upper GI cancer

Inflammatory bowel disease

Gut microbiota

Endoscopy

Colon

Pancreas

Hepatology

JournalScan

PostScript

Editor’s quiz: GI snapshot

Issue Information

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Table of contents

February 2020 - Volume 69 - 2

Commentary

Endoscopy news

Guidelines

Oesophagus

Stomach

Upper GI cancer

Inflammatory bowel disease

Gut microbiota

Endoscopy

Colon

Pancreas

Hepatology

JournalScan

PostScript

Editor’s quiz: GI snapshot

Issue Information