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  • Introduction of anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases: a population-based interrupted time series study

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Inflammatory bowel disease
Original research
Introduction of anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases: a population-based interrupted time series study

Authors

  • Sanjay K Murthy Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada Division of Gastroenterology, The Ottawa Hospital IBD Centre, Ottawa, Ontario, Canada Clinical Epidemiology Program, OttawaHospital Research Institute, Ottawa, Ontario, Canada School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Jahanara Begum ICES uOttawa, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Eric I Benchimol School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada ICES uOttawa, Ottawa, Ontario, Canada Children’sHospital of Eastern Ontario (CHEO) Inflammatory Bowel Disease Centre, Divisionof Gastroenterology, Hepatology and Nutrition, Ottawa, Ontario, Canada Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada CHEOResearch Institute, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Charles N Bernstein Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada Health Sciences Centre Winnipeg, Winnipeg, Manitoba, Canada PubMed articlesGoogle scholar articles
  • Gilaad G Kaplan Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada Foothills Medical Centre, Division of Gastroenterology and Hepatology, Calgary, Alberta, Canada PubMed articlesGoogle scholar articles
  • Jeffrey D McCurdy Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada Division of Gastroenterology, The Ottawa Hospital IBD Centre, Ottawa, Ontario, Canada Clinical Epidemiology Program, OttawaHospital Research Institute, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  • Harminder Singh Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada Health Sciences Centre Winnipeg, Winnipeg, Manitoba, Canada PubMed articlesGoogle scholar articles
  • Laura Targownik Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada Health Sciences Centre Winnipeg, Winnipeg, Manitoba, Canada PubMed articlesGoogle scholar articles
  • Monica Taljaard Clinical Epidemiology Program, OttawaHospital Research Institute, Ottawa, Ontario, Canada School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Sanjay K Murthy, Department of Medicine, The Ottawa Hospital, University of Ottaw, Ottawa, Ontario K1H 8L6, Canada; smurthy{at}toh.ca
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Citation

Murthy SK, Begum J, Benchimol EI, et al
Introduction of anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases: a population-based interrupted time series study
Gut 2020;69:274-282.

Publication history

  • Received February 2, 2019
  • Revised April 23, 2019
  • Accepted April 23, 2019
  • First published June 12, 2019.
Online issue publication 
January 07, 2020

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.