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We read with interest the findings of Frolkis et al and welcome the contribution to this challenging field of research.1 An important consideration in the methodology used is the case definition of incident depression, defined as any patient with a code for a depressive disorder in The Health Improvement Network (THIN) database between 1986 and 2012. The authors acknowledge …
Contributors All co-authors contributed to this letter.
Funding This study was funded by Crohn’s and Colitis UK and National Institute for Health Research.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.
Patient consent for publication Not required.
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