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A 71-year-old man attended accident and emergency with a 1-day history of rectal bleeding without associated abdominal pain, change in bowel habit or history of GI disease. On admission, his haemoglobin was normal at 147 g/L with normal platelets of 194×109/L. There was a raised white blood cell count of 12.2×109/L (normal range 4.5−11×109/L) and normal C-reactive protein of 2.2 mg/L. His urea and electrolytes and liver function tests were normal. The patient had no recent changes to his regular medication and did not take non-steroidal anti-inflammatory drugs, antiplatelet or anticoagulant medications. He reported feeling well with no fevers or weight loss and denied any previous similar episodes. He had recently undergone a minimally …
Contributors MHB and MAS drafted the manuscript, which SM and SMc reviewed for important intellectual content. All the authors reviewed and edited the final article.
Competing interests MHB: None. MAS: Advisory fees: Takeda, Janssen and Falk. Lecture fees: Takeda, MSD, Janssen and Falk. SM: None. SMc: Advisory fees: Abbvie and MSD.
Patient consent for publication Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.