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LW, ZZ and JS contributed equally.
Contributors Concept of the study: LinW, LingW and HJ. Collection and experiment of clinical samples: LinW, ZZ, JS, HZ, YY, ZL and QH. Interpretation of data: LinW and ZZ. Drafting of manuscript: LinW, LingW, ZZ, WH, HZ, YW and HJ.
Funding This study was funded by the National Science Foundation of China (grant no. 81772175).
Competing interests None declared.
Ethics approval The study has been reviewed and approved by the Ethical Committee of Peking University Third Hospital.
Provenance and peer review Not commissioned; internally peer reviewed.
Patient consent for publication Not required.
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