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QH and MY are joint first authors.
Contributors JY had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Concept and design: JY and YP. Acquisition, analysis or interpretation of data: All authors. Drafting of the manuscript: QH and MY. Critical revision of the manuscript for important intellectual content: all authors. Statistical analysis: JY and QH. Obtained funding: JY and YP. Administrative, technical or material support: JY and YP. Supervision: JY and YP.
Funding This work was supported by the startup grant for the 100 Top Talents Program, The Seventh Affiliated Hospital, Sun Yat-sen University (392012), the Youth Program of National Natural Science Foundation of China (82003524) and the National Key Research and Development Program (2018YFA0902801).
Competing interests None declared.
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