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Inflammatory bowel disease
Original research
Whole exome sequencing analyses reveal gene–microbiota interactions in the context of IBD

Authors

  • Shixian Hu Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Arnau Vich Vila Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Ranko Gacesa Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Valerie Collij Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Christine Stevens Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Jack M Fu Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Isaac Wong Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Michael E Talkowski Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA Division of Medical Sciences, Harvard Medical School, Boston, Massachusetts, USA Stanley Center for Psychiatric Research, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Manuel A Rivas Department of Biomedical Data Science, Stanford University, Stanford, California, USA PubMed articlesGoogle scholar articles
  • Floris Imhann Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Laura Bolte Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Hendrik van Dullemen Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Gerard Dijkstra Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Marijn C Visschedijk Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Eleonora A Festen Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Ramnik J Xavier Center for Microbiome Informatics and Therapeutic, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Jingyuan Fu Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands Department of Pediatrics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Mark J Daly Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Cisca Wijmenga Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Alexandra Zhernakova Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Alexander Kurilshikov Department of Genetics, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Rinse K Weersma Department of Gastroenterology and Hepatology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Rinse K Weersma; r.k.weersma{at}mdl.umcg.nl
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Citation

Hu S, Vich Vila A, Gacesa R, et al
Whole exome sequencing analyses reveal gene–microbiota interactions in the context of IBD
Gut 2021;70:285-296.

Publication history

  • Received August 23, 2019
  • Revised April 8, 2020
  • Accepted April 20, 2020
  • First published July 10, 2020.
Online issue publication 
January 07, 2021

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.