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ACM and SK are joint first authors.
CJR and CJS are joint senior authors.
Twitter @DrChrisLamb, @BottProf
Contributors AM, AN, CS and CAL recruited volunteers and analysed samples. SK, MH, LS, JH and CJR designed the study. All authors contributes to study design, analysis of results and edited the article. CJR and CS led the work and wrote first and last drafts of the article.
Funding This research was funded as part of COLOCOHORT research grant from Guts UK AMRC charity.
Competing interests CJR has received grant funding from ARC medical, Norgine, Olympus. He was an expert witness for ARC medical. CJR and LS have received grant funding from 3D Matrix. CAL receives research support from Genentech. CS has performed consultancy for Astarte Medical.
Patient and public involvement Patients and/or the public were involved in the design, or conduct, or reporting, or dissemination plans of this research. Refer to the Methods section for further details.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; internally peer reviewed.
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