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Inflammatory bowel disease
Original research
SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation

Authors

  • Lea Južnić Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany Center for Regenerative Therapies (CRTD), Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Kenneth Peuker Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany Center for Regenerative Therapies (CRTD), Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Anne Strigli Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany Center for Regenerative Therapies (CRTD), Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Mario Brosch Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany Center for Regenerative Therapies (CRTD), Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Alexander Herrmann Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany Center for Regenerative Therapies (CRTD), Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Robert Häsler Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel, Germany PubMed articlesGoogle scholar articles
  • Michael Koch Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany Center for Regenerative Therapies (CRTD), Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Liz Matthiesen Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany Center for Regenerative Therapies (CRTD), Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Yvonne Zeissig Department of General Pediatrics, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Britt-Sabina Löscher Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel, Germany PubMed articlesGoogle scholar articles
  • Alexander Nuber Division of Molecular Biology, Biomedical Center, Faculty of Medicine, Ludwig Maximilians University Munich, Munich, Germany PubMed articlesGoogle scholar articles
  • Gunnar Schotta Division of Molecular Biology, Biomedical Center, Faculty of Medicine, Ludwig Maximilians University Munich, Munich, Germany PubMed articlesGoogle scholar articles
  • Volker Neumeister Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Triantafyllos Chavakis Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Thomas Kurth Center for Molecular and Cellular Bioengineering (CMBC), Technology Platform, Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Mathias Lesche DRESDEN-concept Genome Center, c/o Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Andreas Dahl DRESDEN-concept Genome Center, c/o Center for Molecular and Cellular Bioengineering (CMCB), Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Anne von Mässenhausen BIOTEChnology Center, Technische Universität (TU) Dresden, Dresden, Germany Division of Nephrology, Department of Medicine III, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Andreas Linkermann BIOTEChnology Center, Technische Universität (TU) Dresden, Dresden, Germany Division of Nephrology, Department of Medicine III, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Stefan Schreiber Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel, Germany Department of Internal Medicine I, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany PubMed articlesGoogle scholar articles
  • Konrad Aden Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel, Germany Department of Internal Medicine I, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany PubMed articlesGoogle scholar articles
  • Philip C Rosenstiel Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel, Germany PubMed articlesGoogle scholar articles
  • Andre Franke Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Christian-Albrechts-University of Kiel, Kiel, Germany PubMed articlesGoogle scholar articles
  • Jochen Hampe Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany Center for Regenerative Therapies (CRTD), Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  • Sebastian Zeissig Department of Medicine I, University Medical Center Dresden, Technische Universität (TU) Dresden, Dresden, Germany Center for Regenerative Therapies (CRTD), Technische Universität (TU) Dresden, Dresden, Germany PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Sebastian Zeissig, Department of Medicine I, University Medical Center Dresden, and Center for Regenerative Therapies Dresden (CRTD), Technische Universität (TU) Dresden, 01307 Dresden, Germany; sebastian.zeissig{at}tu-dresden.de
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Citation

Južnić L, Peuker K, Strigli A, et al
SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation
Gut 2021;70:485-498.

Publication history

  • Received April 6, 2020
  • Revised May 5, 2020
  • Accepted May 12, 2020
  • First published June 5, 2020.
Online issue publication 
May 24, 2021

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.