Alpha-1 antitrypsin governs alcohol-related liver disease in mice and humans

Christoph Grander; Benedikt Schaefer; Julian Schwärzler; Felix Grabherr; Dennis M de Graaf; Barbara Enrich; Georg Oberhuber; Lisa Mayr; Moris Sangineto; Nikolai Jaschke; Timon E Adolph; Maria Effenberger; Alexander R Moschen; Charles A Dinarello; Heinz Zoller; Herbert Tilg

doi:10.1136/gutjnl-2020-321375

Article info

Hepatology

Original research

Alpha-1 antitrypsin governs alcohol-related liver disease in mice and humans

Authors

Christoph Grander Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Benedikt Schaefer Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Julian Schwärzler Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Felix Grabherr Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Dennis M de Graaf Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA PubMed articles Google scholar articles
Barbara Enrich Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Georg Oberhuber INNPATH, Institute of Pathology, University Hospital of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Lisa Mayr Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Moris Sangineto Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Nikolai Jaschke Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Timon E Adolph Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Maria Effenberger Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Alexander R Moschen Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Charles A Dinarello Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA PubMed articles Google scholar articles
Heinz Zoller Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles
Herbert Tilg Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, Austria PubMed articles Google scholar articles

Correspondence to Professor Herbert Tilg, Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology & Metabolism, Medical University Innsbruck, Innsbruck 6020, Austria; herbert.tilg{at}i-med.ac.at

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Citation

Grander C, Schaefer B, Schwärzler J, et al

Alpha-1 antitrypsin governs alcohol-related liver disease in mice and humans

Gut 2021;70:585-594.

Publication history

Received April 8, 2020
Revised June 10, 2020
Accepted June 11, 2020
First published July 22, 2020.

Online issue publication

February 05, 2021

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