Footnotes

• Contributors RZ and Q-YW contributed equally in this study. RZ, Q-YW, YW, YW, Y-PC and XS collected and analysed the data. Q-YW and RZ wrote the manuscript under the guidance of XTW. All the authors have read manuscript, and XTW approved the final manuscript.

• Funding This work was supported by Sichuan Province Science and Technology Support Project (2018SZ0189).

• Competing interests None declared.

• Patient consent for publication Not required.

• Provenance and peer review Not commissioned; externally peer reviewed.