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Towards personalised management for non-variceal upper gastrointestinal bleeding
  1. Joseph J Y Sung1,
  2. Loren Laine2,
  3. Ernst J Kuipers3,
  4. Alan N Barkun4
  1. 1 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
  2. 2 Section of Digestive Diseases, Yale School of Medicine and VA Connecticut Healthcare System, New Haven, Connecticut, USA
  3. 3 Erasmus University Medical Center, Rotterdam, The Netherlands
  4. 4 Gastroenterology, McGILL University health centre, Montreal, Quebec, Canada
  1. Correspondence to Professor Joseph J Y Sung, The Chinese University of Hong Kong, Hong Kong, Hong Kong; josephsung{at}


Guidelines from national and international professional societies on upper gastrointestinal bleeding highlight the important clinical issues but do not always identify specific management strategies pertaining to individual patients. Optimal treatment should consider the personal needs of an individual patient and the pertinent resources and experience available at the point of care. This article integrates international guidelines and consensus into three stages of management: pre-endoscopic assessment and treatment, endoscopic evaluation and haemostasis and postendoscopic management. We emphasise the need for personalised management strategies based on patient characteristics, nature of bleeding lesions and the clinical setting including available resources.

  • gastrointestinal bleeding
  • endoscopic procedures
  • non-steroidal anti-inflammatory drugs
  • helicobacter pylori

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  • Contributors JJYS initiated the project, draft the manuscript and approved final paper. LL, EJK and ANB contributed in the content, writing, diagram and approved the final paper.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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