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Contributors NA and MBB conceived and designed the study. MBB analysed the data, with input from NA. AT, CN and LA helped interpret the results. AT and MBB drafted the manuscript, and NA, CN and LA revised it for important intellectual content. All authors approved the final version for publication.
Funding This work was supported by Grant 6D02363004 from the Public Health Agency of Canada, and by Career Awards 34695 (NA) and 267222 (AT) from the Fonds de recherche du Québec-Santé.
Competing interests None declared.
Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.
Provenance and peer review Not commissioned; internally peer reviewed.