Blocking VCAM-1 inhibits pancreatic tumour progression and cancer-associated thrombosis/thromboembolism

Makoto Sano; Ryota Takahashi; Hideaki Ijichi; Kazunaga Ishigaki; Tomoharu Yamada; Koji Miyabayashi; Gen Kimura; Suguru Mizuno; Hiroyuki Kato; Hiroaki Fujiwara; Takuma Nakatsuka; Yasuo Tanaka; Jinsuk Kim; Yohei Masugi; Yasuyuki Morishita; Mariko Tanaka; Tetsuo Ushiku; Yousuke Nakai; Keisuke Tateishi; Yukimoto Ishii; Hiroyuki Isayama; Harold L Moses; Kazuhiko Koike

doi:10.1136/gutjnl-2020-320608

Article info

Pancreas

Original research

Blocking VCAM-1 inhibits pancreatic tumour progression and cancer-associated thrombosis/thromboembolism

Authors

Makoto Sano Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan Division of Medical Research Planning and Development, Nihon University School of Medicine, Tokyo, Japan PubMed articles Google scholar articles
Ryota Takahashi Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Hideaki Ijichi Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan Clinical Nutrition Center, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Kazunaga Ishigaki Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Tomoharu Yamada Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Koji Miyabayashi Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Gen Kimura Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Suguru Mizuno Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Hiroyuki Kato Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Hiroaki Fujiwara Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Takuma Nakatsuka Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Yasuo Tanaka Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Jinsuk Kim Division of Medical Research Planning and Development, Nihon University School of Medicine, Tokyo, Japan PubMed articles Google scholar articles
Yohei Masugi Department of Pathology, Keio University School of Medicine, Tokyo, Japan PubMed articles Google scholar articles
Yasuyuki Morishita Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Mariko Tanaka Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Tetsuo Ushiku Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Yousuke Nakai Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan Department of Endoscopy and Endoscopic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Keisuke Tateishi Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Yukimoto Ishii Division of Medical Research Planning and Development, Nihon University School of Medicine, Tokyo, Japan PubMed articles Google scholar articles
Hiroyuki Isayama Department of Gastoroenterology, Juntendo University School of Medicine, Tokyo, Japan PubMed articles Google scholar articles
Harold L Moses Department of Cancer Biology, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee, USA PubMed articles Google scholar articles
Kazuhiko Koike Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles

Correspondence to Dr Hideaki Ijichi, Department of Gastroenterology, The University of Tokyo Graduate School of Medicine Faculty of Medicine, Tokyo 113-8655, Japan; hideijichi-gi{at}umin.ac.jp

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Citation

Sano M, Takahashi R, Ijichi H, et al

Blocking VCAM-1 inhibits pancreatic tumour progression and cancer-associated thrombosis/thromboembolism

Gut 2021;70:1713-1723.

Publication history

Received January 6, 2020
Revised October 1, 2020
Accepted October 3, 2020
First published October 21, 2020.

Online issue publication

August 06, 2021

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