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Hepatology
Original research
Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis

Authors

  • Gabriel Mezzano Liver Unit, Hospital Clinic de Barcelona, Barcelona, Catalunya, Spain Gastroenterología - Hepatología, Hospital del Salvador. Universidad de Chile, Santiago, Chile PubMed articlesGoogle scholar articles
  • Adria Juanola Liver Unit, Hospital Clinic de Barcelona, Barcelona, Catalunya, Spain Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain Centro de Investigacion Biomedica en Red Enfermedades Hepaticas y Digestivas (CIBERehd), Madrid, Spain PubMed articlesGoogle scholar articles
  • Andres Cardenas Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain Centro de Investigacion Biomedica en Red Enfermedades Hepaticas y Digestivas (CIBERehd), Madrid, Spain Institute of Digestive Disease and Metabolism, Hospital Clinic de Barcelona, Barcelona, Catalunya, Spain PubMed articlesGoogle scholar articles
  • Esteban Mezey Division of Gastroenterology and Hepatology. Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • James P Hamilton Division of Gastroenterology and Hepatology. Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Elisa Pose Liver Unit, Hospital Clinic de Barcelona, Barcelona, Catalunya, Spain Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain Centro de Investigacion Biomedica en Red Enfermedades Hepaticas y Digestivas (CIBERehd), Madrid, Spain PubMed articlesGoogle scholar articles
  • Isabel Graupera Liver Unit, Hospital Clinic de Barcelona, Barcelona, Catalunya, Spain Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain Centro de Investigacion Biomedica en Red Enfermedades Hepaticas y Digestivas (CIBERehd), Madrid, Spain Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Catalunya, Spain PubMed articlesGoogle scholar articles
  • Pere Ginès Liver Unit, Hospital Clinic de Barcelona, Barcelona, Catalunya, Spain Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain Centro de Investigacion Biomedica en Red Enfermedades Hepaticas y Digestivas (CIBERehd), Madrid, Spain Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Catalunya, Spain PubMed articlesGoogle scholar articles
  • Elsa Solà Liver Unit, Hospital Clinic de Barcelona, Barcelona, Catalunya, Spain Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain Centro de Investigacion Biomedica en Red Enfermedades Hepaticas y Digestivas (CIBERehd), Madrid, Spain Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Catalunya, Spain PubMed articlesGoogle scholar articles
  • Ruben Hernaez Gastroenterology and Hepatology, Depatment of Medicine, Baylor College of Medicine, Houston, Texas, USA Section of Gastroenterology, Michael E DeBakey Veterans Affairs Medical Center, Houston, Texas, USA Center for Innovation in Quality, Effectiveness and Safety (IQuESt), Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Ruben Hernaez, Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA; ruben.hernaez{at}bcm.edu
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Citation

Mezzano G, Juanola A, Cardenas A, et al
Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis
Gut 2022;71:148-155.

Publication history

  • Received June 10, 2020
  • Revised December 22, 2020
  • Accepted December 23, 2020
  • First published January 12, 2021.
Online issue publication 
February 02, 2022

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© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.