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Hepatology
Original research
Unannotated small RNA clusters associated with circulating extracellular vesicles detect early stage liver cancer

Authors

  • Johann von Felden Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA Department of Medicine, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany PubMed articlesGoogle scholar articles
  • Teresa Garcia-Lezana Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Navneet Dogra Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA IBM Thomas J Watson Research Center, Yorktown Heights, New York, USA PubMed articlesGoogle scholar articles
  • Edgar Gonzalez-Kozlova Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Mehmet Eren Ahsen Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Amanda Craig Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Stacey Gifford IBM Thomas J Watson Research Center, Yorktown Heights, New York, USA PubMed articlesGoogle scholar articles
  • Benjamin Wunsch IBM Thomas J Watson Research Center, Yorktown Heights, New York, USA PubMed articlesGoogle scholar articles
  • Joshua T Smith IBM Thomas J Watson Research Center, Yorktown Heights, New York, USA PubMed articlesGoogle scholar articles
  • Sungcheol Kim IBM Thomas J Watson Research Center, Yorktown Heights, New York, USA PubMed articlesGoogle scholar articles
  • Jennifer E L Diaz Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Xintong Chen Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Ismail Labgaa Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA Department of Visceral Surgery, Lausanne University Hospital, Lausanne, Switzerland PubMed articlesGoogle scholar articles
  • Philipp Haber Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Reena Olsen Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Dan Han Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Paula Restrepo Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Delia D'Avola Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA Liver Unit and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Clínica Universidad de Navarra, Pamplona, Spain PubMed articlesGoogle scholar articles
  • Gabriela Hernandez-Meza Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Kimaada Allette Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Robert Sebra Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA Sema4, Stamford, Connecticut, USA PubMed articlesGoogle scholar articles
  • Behnam Saberi Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Parissa Tabrizian Recanati/Miller Transplantation Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA Department of Surgery, Mount Sinai School of Medicine, New York, New York, USA PubMed articlesGoogle scholar articles
  • Amon Asgharpour Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Douglas Dieterich Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Josep M. Llovet Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA Liver Cancer Translational Research Laboratory, BCLC Group, IDIBAPS, CIBEREHD, Hospital Clinic, Universitat de Barcelona, Barcelona, Catalonia, Spain Institució Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia, Spain PubMed articlesGoogle scholar articles
  • Carlos Cordon-Cardo Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Ash Tewari Department of Urology, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Myron Schwartz Department of Surgery, Mount Sinai School of Medicine, New York, New York, USA PubMed articlesGoogle scholar articles
  • Gustavo Stolovitzky Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA IBM Thomas J Watson Research Center, Yorktown Heights, New York, USA PubMed articlesGoogle scholar articles
  • Bojan Losic Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, New York, USA Diabetes, Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  • Augusto Villanueva Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA Division of Hematology and Medical Oncology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Augusto Villanueva, Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; augusto.villanueva{at}mssm.edu; Dr Gustavo Stolovitzky, Sema4, Stamford, CT 06902, USA; gustavo.stolovitzky{at}sema4.com; Dr Bojan Losic; blosic{at}gmail.com
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Citation

von Felden J, Garcia-Lezana T, Dogra N, et al
Unannotated small RNA clusters associated with circulating extracellular vesicles detect early stage liver cancer
Gut 2022;71:2069-2080.

Publication history

  • Received April 26, 2021
  • Accepted July 15, 2021
  • First published July 28, 2021.
Online issue publication 
September 07, 2022

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© Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.