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We read with interest the important article by Pan CQ and colleagues, wherein they demonstrated the long-term safety of infants whose mothers were treated with tenofovir disoproxil fumarate (TDF) during pregnancy.1 However, we feel that the findings are not universally applicable and may not have an influence on clinical practice.
In this study, infants were exposed to TDF for a short median duration of 8.2 weeks. It is known that the adverse effects of TDF on bone mineral density (BMD) …
Contributors AJ and AKV: drafter and edited the file. GD: literature review.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.