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Braf mutation induces rapid neoplastic transformation in the aged and aberrantly methylated intestinal epithelium

Authors

  • Lochlan Fennell The Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, AustraliaFaculty of Medicine, The University of Queensland, Saint Lucia, Queensland, Australia PubMed articlesGoogle scholar articles
  • Alexandra Kane The Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, AustraliaFaculty of Medicine, The University of Queensland, Saint Lucia, Queensland, AustraliaConjoint Internal Medical Laboratory, Chemical Pathology, Health Support Queensland Pathology Queensland, Herston, Queensland, Australia PubMed articlesGoogle scholar articles
  • Cheng Liu The Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, AustraliaFaculty of Medicine, The University of Queensland, Saint Lucia, Queensland, Australia PubMed articlesGoogle scholar articles
  • Diane McKeone The Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia PubMed articlesGoogle scholar articles
  • Gunter Hartel Statistics Department, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia PubMed articlesGoogle scholar articles
  • Chang Su The Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, AustraliaFaculty of Medicine, The University of Queensland, Saint Lucia, Queensland, Australia PubMed articlesGoogle scholar articles
  • Catherine Bond The Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, AustraliaFaculty of Medicine, The University of Queensland, Saint Lucia, Queensland, Australia PubMed articlesGoogle scholar articles
  • Mark Bettington Envoi Specialist Pathologists, Brisbane, Queensland, Australia PubMed articlesGoogle scholar articles
  • Barbara Leggett The Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, AustraliaFaculty of Medicine, The University of Queensland, Saint Lucia, Queensland, AustraliaDepartment of Gastroenterology and Hepatology, The Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia PubMed articlesGoogle scholar articles
  • Vicki Whitehall The Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, AustraliaFaculty of Medicine, The University of Queensland, Saint Lucia, Queensland, AustraliaConjoint Internal Medical Laboratory, Chemical Pathology, Health Support Queensland Pathology Queensland, Herston, Queensland, Australia PubMed articlesGoogle scholar articles
  1. Correspondence to Mr Lochlan Fennell, The Conjoint Gastroenterology Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia; Lochlan.Fennell{at}qimrberghofer.edu.au
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Citation

Fennell L, Kane A, Liu C, et al
Braf mutation induces rapid neoplastic transformation in the aged and aberrantly methylated intestinal epithelium
Gut 2022;71:1127-1140.

Publication history

  • Received June 10, 2020
  • Accepted June 30, 2021
  • First published July 6, 2021.
Online issue publication 
October 18, 2023

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.