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  • Lineage tracing and single-cell analysis reveal proliferative Prom1+ tumour-propagating cells and their dynamic cellular transition during liver cancer progression

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Hepatology
Original research
Lineage tracing and single-cell analysis reveal proliferative Prom1+ tumour-propagating cells and their dynamic cellular transition during liver cancer progression

Authors

  • Lei Zhou School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China PubMed articlesGoogle scholar articles
  • Ken HO Yu School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China Laboratory of Data Discovery for Health Limited (D24H), Hong Kong Science Park, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  • Tin Lok Wong School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  • Zhao Zhang Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  • Chun Ho Chan School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  • Jane HC Loong School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  • Noelia Che School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  • Hua Jian Yu School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  • Kel Vin Tan Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  • Man Tong School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  • Elly S Ngan Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  • Joshua WK Ho School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China Laboratory of Data Discovery for Health Limited (D24H), Hong Kong Science Park, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  • Stephanie Ma School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong SAR, China PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Stephanie Ma, School of Biomedical Sciences, The University of Hong Kong, Hong Kong, Hong Kong; stefma{at}hku.hk; Dr Joshua WK Ho, School of Biomedical Sciences, The University of Hong Kong, Hong Kong, Hong Kong; jwkho{at}hku.hk
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Citation

Zhou L, Yu KH, Wong TL, et al
Lineage tracing and single-cell analysis reveal proliferative Prom1+ tumour-propagating cells and their dynamic cellular transition during liver cancer progression
Gut 2022;71:1656-1668.

Publication history

  • Received February 4, 2021
  • Accepted September 19, 2021
  • First published September 29, 2021.
Online issue publication 
July 07, 2022

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