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  • Undiagnosed inflammatory bowel disease among individuals undergoing colorectal cancer screening: a nationwide Danish cohort study 2014–2018

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Undiagnosed inflammatory bowel disease among individuals undergoing colorectal cancer screening: a nationwide Danish cohort study 2014–2018
  1. Tine Jess1,2,
  2. Marie V Vestergaard1,
  3. Aske T Iversen1,
  4. Kristine Højgaard Allin1,2
  1. 1 Center for Molecular Prediction of Inflammatory Bowel Disease, PREDICT, Department of Clinical Medicine, Aalborg Universitet, Copenhagen, Denmark
  2. 2 Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark
  1. Correspondence to Dr Tine Jess, Center for Molecular Prediction of Inflammatory Bowel Disease, PREDICT, Department of Clinical Medicine, Aalborg Universitet, Copenhagen, Denmark; jess{at}dcm.aau.dk

https://doi.org/10.1136/gutjnl-2022-327296

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    Chiu et al recently investigated the long-term effectiveness of national faecal immunochemical test (FIT) screening for colorectal cancer (CRC).1 They demonstrated reduced risk of advanced-stage CRC and its mortality with larger reductions in distal CRC as compared with proximal CRC. An additional outcome of the CRC screening programme may be early detection of other diseases, such as inflammatory bowel diseases (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD). The prevalence of IBD is up to 1% in westernised countries.2 3 However, symptoms of IBD vary and may increase time to diagnosis.4 Correct and early diagnosis is important to improve treatment outcomes and patients’ quality of life.5 Although early markers of IBD, such as antimicrobial antibodies and serum proteins, are emerging,6 7 colonoscopy still remains one of the only methods to detect early …

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    Footnotes

    • Twitter @PREDICTIBD, @KristineAllin

    • Contributors Overall responsible and guarantor: TJ. Study design: TJ and ATI. Statistical analyses: ATI. Interpretation of results: TJ, ATI, MVV and KHA. Manuscript writing: TJ, MVV. Revision of the manuscript and acceptance of final version: TJ, ATI, MVV and KHA.

    • Funding The work was supported by a research grant from the Danish National Research Foundation, grant no. DNRF148.

    • Disclaimer The funding agency had no role in the conduct of the study.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.