Article info

Original research
Gut virome-colonising Orthohepadnavirus genus is associated with ulcerative colitis pathogenesis and induces intestinal inflammation in vivo

Authors

  • Luca Massimino Department of Gastroenterology and Digestive Endoscopy, IRCCS Ospedale San Raffaele, Milano, Italy Division of Immunology, Transplantation and Infectious Disease, IRCCS Ospedale San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Orazio Palmieri Division of Gastroenterology and Endoscopy, Fondazione IRCCS “Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy PubMed articlesGoogle scholar articles
  • Amanda Facoetti Division of Immunology, Transplantation and Infectious Disease, IRCCS Ospedale San Raffaele, Milano, Italy Faculty of Medicine, Università Vita Salute San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Davide Fuggetta Division of Immunology, Transplantation and Infectious Disease, IRCCS Ospedale San Raffaele, Milano, Italy Faculty of Medicine, Università Vita Salute San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Salvatore Spanò Department of Gastroenterology and Digestive Endoscopy, IRCCS Ospedale San Raffaele, Milano, Italy Division of Immunology, Transplantation and Infectious Disease, IRCCS Ospedale San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Luigi Antonio Lamparelli IBD Center, IRCCS Humanitas Research Hospital, Rozzano, Italy Department of Biomedical Sciences, Humanitas University, Milan, Italy PubMed articlesGoogle scholar articles
  • Silvia D'Alessio PhoenixLAB, Lodi, Italy PubMed articlesGoogle scholar articles
  • Stefania Cagliani Division of Immunology, Transplantation and Infectious Disease, IRCCS Ospedale San Raffaele, Milano, Italy Faculty of Medicine, Università Vita Salute San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Federica Furfaro Department of Gastroenterology and Digestive Endoscopy, IRCCS Ospedale San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Ferdinando D'Amico Department of Gastroenterology and Digestive Endoscopy, IRCCS Ospedale San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Alessandra Zilli Department of Gastroenterology and Digestive Endoscopy, IRCCS Ospedale San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Gionata Fiorino Department of Gastroenterology and Digestive Endoscopy, IRCCS Ospedale San Raffaele, Milano, Italy Faculty of Medicine, Università Vita Salute San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Tommaso Lorenzo Parigi Department of Gastroenterology and Digestive Endoscopy, IRCCS Ospedale San Raffaele, Milano, Italy Faculty of Medicine, Università Vita Salute San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Daniele Noviello Department of Pathophysiology and Transplantation, University of Milan, Milano, Italy PubMed articlesGoogle scholar articles
  • Anna Latiano Division of Gastroenterology and Endoscopy, Fondazione IRCCS “Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy PubMed articlesGoogle scholar articles
  • Fabrizio Bossa Division of Gastroenterology and Endoscopy, Fondazione IRCCS “Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy PubMed articlesGoogle scholar articles
  • Tiziana Latiano Division of Gastroenterology and Endoscopy, Fondazione IRCCS “Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy PubMed articlesGoogle scholar articles
  • Alessandra Pirola GalSeq s.r.l, Milan, Italy PubMed articlesGoogle scholar articles
  • Luca Mologni Department of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy PubMed articlesGoogle scholar articles
  • Rocco Giovanni Piazza Department of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy Hematology and Clinical Research Unit, San Gerardo Hospital, Monza, Italy PubMed articlesGoogle scholar articles
  • Danilo Abbati Division of Immunology, Transplantation and Infectious Disease, IRCCS Ospedale San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Francesco Perri Division of Gastroenterology and Endoscopy, Fondazione IRCCS “Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy PubMed articlesGoogle scholar articles
  • Chiara Bonini Division of Immunology, Transplantation and Infectious Disease, IRCCS Ospedale San Raffaele, Milano, Italy Faculty of Medicine, Università Vita Salute San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Laurent Peyrin-Biroulet Inserm NGERE, University of Lorraine, Nancy, France Department of Hepato-Gastroenterology, University Hospital Centre Nancy, Nancy, France PubMed articlesGoogle scholar articles
  • Alberto Malesci Department of Gastroenterology and Digestive Endoscopy, IRCCS Ospedale San Raffaele, Milano, Italy Faculty of Medicine, Università Vita Salute San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Vipul Jairath Department of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada PubMed articlesGoogle scholar articles
  • Silvio Danese Department of Gastroenterology and Digestive Endoscopy, IRCCS Ospedale San Raffaele, Milano, Italy Division of Immunology, Transplantation and Infectious Disease, IRCCS Ospedale San Raffaele, Milano, Italy Faculty of Medicine, Università Vita Salute San Raffaele, Milano, Italy PubMed articlesGoogle scholar articles
  • Federica Ungaro Department of Gastroenterology and Digestive Endoscopy, IRCCS Ospedale San Raffaele, Milano, Italy Division of Immunology, Transplantation and Infectious Disease, IRCCS Ospedale San Raffaele, Milano, Italy Faculty of Medicine, Università Vita Salute San Raffaele, Milano, Italy Department of Biomedical Sciences, Humanitas University, Milan, Italy PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Federica Ungaro, Department of Gastroenterology and Digestive Endoscopy, Division of Immunology, Transplantation and Infectious Disease, IRCCS Ospedale San Raffaele, Milano, 20132, Italy; ungaro.federica{at}hsr.it
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Citation

Massimino L, Palmieri O, Facoetti A, et al
Gut virome-colonising Orthohepadnavirus genus is associated with ulcerative colitis pathogenesis and induces intestinal inflammation in vivo

Publication history

  • Received July 29, 2022
  • Accepted February 6, 2023
  • First published February 14, 2023.
Online issue publication 
October 29, 2023

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