Gut: 72 (2)

Commentaries

Epithelial RAC1 niches in IBD: from barrier integrity to cytoskeletal plasticity (11 April, 2022)
Lea-Maxie Haag, Britta Siegmund
LOXL2 in pancreatic tumourigenesis: the complexity of tumour–stromal crosstalk exemplified (15 April, 2022)
Seth B Coffelt, Jennifer P Morton

Endoscopy news

Health-code-based triage versus universal COVID-19 PCR testing before endoscopy in a low incidence area: a real-world experience (9 November, 2022)
Zhihui Duan, Dengxiang Liu, Shengyun Zhou, Hui Li, Xiaofang Sun, Chunqian Zhao, Qiong Duan, Liwei Li, Xiaochong Zhang, Lingxuan Jin

Stomach

Original research: Regulatory enhancer profiling of mesenchymal-type gastric cancer reveals subtype-specific epigenomic landscapes and targetable vulnerabilities (11 July, 2022)
Shamaine Wei Ting Ho, Taotao Sheng, Manjie Xing, Wen Fong Ooi, Chang Xu, Raghav Sundar, Kie Kyon Huang, Zhimei Li, Vikrant Kumar, Kalpana Ramnarayanan, Feng Zhu, Supriya Srivastava, Zul Fazreen Bin Adam Isa, Chukwuemeka George Anene-Nzelu, Milad Razavi-Mohseni, Dustin Shigaki, Haoran Ma, Angie Lay Keng Tan, Xuewen Ong, Ming Hui Lee, Su Ting Tay, Yu Amanda Guo, Weitai Huang, Shang Li, Michael A. Beer, Roger Sik Yin Foo, Ming Teh, Anders Jacobsen Skanderup, Bin Tean Teh, Patrick Tan
Original research: Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid models (15 June, 2022)
Yin Tong, Priscilla S W Cheng, Chung Sze Or, Sarah S K Yue, Hoi Cheong Siu, Siu Lun Ho, Simon Y K Law, Wai Yin Tsui, Dessy Chan, Stephanie Ma, Siu Po Lee, Annie S Y Chan, April S Chan, Shui Wa Yun, Ho Sang Hui, Siu Tsan Yuen, Suet Yi Leung, Helen H N Yan

GI cancer

Original research: Phase II trial of weekly erlotinib dosing to reduce duodenal polyp burden associated with familial adenomatous polyposis (30 May, 2022)
N Jewel Samadder, Nathan Foster, Ryan P McMurray, Carol A Burke, Elena Stoffel, Priyanka Kanth, Rohit Das, Marcia Cruz-Correa, E Vilar, Gautam Mankaney, Navtej Buttar, Selvi Thirumurthi, Danielle K Turgeon, Michael Sossenheimer, Michelle Westover, Ellen Richmond, Asad Umar, Gary Della'Zanna, Luz M Rodriguez, Eva Szabo, David Zahrieh, Paul J Limburg

Inflammatory bowel disease

Original research: Efficacy of biological therapies and small molecules in induction and maintenance of remission in luminal Crohn’s disease: systematic review and network meta-analysis (30 July, 2022)
Brigida Barberio, David J Gracie, Christopher J Black, Alexander C Ford
Original research: Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation (3 March, 2022)
Luz del Carmen Martínez-Sánchez, Phuong Anh Ngo, Rashmita Pradhan, Lukas-Sebastian Becker, David Boehringer, Despina Soteriou, Marketa Kubankova, Christine Schweitzer, Tatyana Koch, Veronika Thonn, Lena Erkert, Iris Stolzer, Claudia Günther, Christoph Becker, Benno Weigmann, Monika Klewer, Christoph Daniel, Kerstin Amann, Stefan Tenzer, Raja Atreya, Martin Bergo, Cord Brakebusch, Alastair J M Watson, Jochen Guck, Ben Fabry, Imke Atreya, Markus F Neurath, Rocío López-Posadas

COVID-19

Vaccine escape, increased breakthrough and reinfection in infliximab-treated patients with IBD during the Omicron wave of the SARS-CoV-2 pandemic (28 July, 2022) Free
Nicholas A Kennedy, Malik Janjua, Neil Chanchlani, Simeng Lin, Claire Bewshea, Rachel Nice, Timothy J McDonald, Cressida Auckland, Lorna W Harries, Merlin Davies, Stephen Michell, Klaartje B Kok, Christopher A Lamb, Philip J Smith, Ailsa L Hart, Richard CG Pollok, Charlie W Lees, Rosemary J Boyton, Daniel M Altmann, Shaji Sebastian, Nicholas Powell, James R Goodhand, Tariq Ahmad

Endoscopy

Original research: Targeted intervention to achieve waste reduction in gastrointestinal endoscopy (19 August, 2022)
João A Cunha Neves, Joana Roseira, Patrícia Queirós, Helena Tavares Sousa, Gianluca Pellino, Miguel F Cunha

Gut microbiota

Original research: 6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in mice (13 June, 2022)
Kassem Makki, Harald Brolin, Natalia Petersen, Marcus Henricsson, Dan Ploug Christensen, Muhammad Tanweer Khan, Annika Wahlström, Per-Olof Bergh, Valentina Tremaroli, Kristina Schoonjans, Hanns-Ulrich Marschall, Fredrik Bäckhed

Colon

Original research: Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases (15 June, 2022)
Kevin M Sullivan, Xiuyun Jiang, Prajna Guha, Christopher Lausted, Jason A Carter, Cynthia Hsu, Kevin P Labadie, Karan Kohli, Heidi L Kenerson, Sara K Daniel, Xiaowei Yan, Changting Meng, Arezou Abbasi, Marina Chan, Y David Seo, James O Park, Ian Nicholas Crispe, Raymond S Yeung, Teresa S Kim, Taranjit S Gujral, Qiang Tian, Steven C Katz, Venu G Pillarisetty
Original research: Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN (8 September, 2022)
Eileen Morgan, Melina Arnold, A Gini, V Lorenzoni, C J Cabasag, Mathieu Laversanne, Jerome Vignat, Jacques Ferlay, Neil Murphy, Freddie Bray

Pancreas

Original research: Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma (15 April, 2022)
Marta Alonso-Nocelo, Laura Ruiz-Cañas, Patricia Sancho, Kıvanç Görgülü, Sonia Alcalá, Coral Pedrero, Mireia Vallespinos, Juan Carlos López-Gil, Marina Ochando, Elena García-García, Sara Maria David Trabulo, Paola Martinelli, Patricia Sánchez-Tomero, Carmen Sánchez-Palomo, Patricia Gonzalez-Santamaría, Lourdes Yuste, Sonja Maria Wörmann, Derya Kabacaoğlu, Julie Earl, Alberto Martin, Fernando Salvador, Sandra Valle, Laura Martin-Hijano, Alfredo Carrato, Mert Erkan, Laura García-Bermejo, Patrick C Hermann, Hana Algül, Gema Moreno-Bueno, Christopher Heeschen, Francisco Portillo, Amparo Cano, Bruno Sainz
Original research: Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer (27 May, 2022)
Maria Chiara De Santis, Luca Gozzelino, Jean Piero Margaria, Andrea Costamagna, Edoardo Ratto, Federico Gulluni, Enza Di Gregorio, Erica Mina, Nicla Lorito, Marina Bacci, Rossano Lattanzio, Gianluca Sala, Paola Cappello, Francesco Novelli, Elisa Giovannetti, Caterina Vicentini, Silvia Andreani, Pietro Delfino, Vincenzo Corbo, Aldo Scarpa, Paolo Ettore Porporato, Andrea Morandi, Emilio Hirsch, Miriam Martini

Hepatology

Original research: Non-alcoholic fatty liver disease and risk of new-onset heart failure: an updated meta-analysis of about 11 million individuals (25 July, 2022)
Alessandro Mantovani, Graziana Petracca, Alessandro Csermely, Giorgia Beatrice, Stefano Bonapace, Andrea Rossi, Herbert Tilg, Christopher D Byrne, Giovanni Targher
Original research:
Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study
(4 July, 2022)
Stephan Buch, Hamish Innes, Philipp Ludwig Lutz, Hans Dieter Nischalke, Jens U Marquardt, Janett Fischer, Karl Heinz Weiss, Jonas Rosendahl, Astrid Marot, Marcin Krawczyk, Markus Casper, Frank Lammert, Florian Eyer, Arndt Vogel, Silke Marhenke, Johann von Felden, Rohini Sharma, Stephen Rahul Atkinson, Andrew McQuillin, Jacob Nattermann, Clemens Schafmayer, Andre Franke, Christian Strassburg, Marcella Rietschel, Heidi Altmann, Stefan Sulk, Veera Raghavan Thangapandi, Mario Brosch, Carolin Lackner, Rudolf E Stauber, Ali Canbay, Alexander Link, Thomas Reiberger, Mattias Mandorfer, Georg Semmler, Bernhard Scheiner, Christian Datz, Stefano Romeo, Stefano Ginanni Corradini, William Lucien Irving, Joanne R Morling, Indra Neil Guha, Eleanor Barnes, M Azim Ansari, Jocelyn Quistrebert, Luca Valenti, Sascha A Müller, Marsha Yvonne Morgan, Jean-François Dufour, Jonel Trebicka, Thomas Berg, Pierre Deltenre, Sebastian Mueller, Jochen Hampe, Felix Stickel
Original research: Accurate liquid biopsy for the diagnosis of non-alcoholic steatohepatitis and liver fibrosis (12 July, 2022)
Giulia Angelini, Simona Panunzi, Lidia Castagneto-Gissey, Francesca Pellicanò, Andrea De Gaetano, Maurizio Pompili, Laura Riccardi, Matteo Garcovich, Marco Raffaelli, Luigi Ciccoritti, Ornella Verrastro, Maria Francesca Russo, Fabio Maria Vecchio, Giovanni Casella, James Casella-Mariolo, Luigi Papa, Pier Luigi Marini, Francesco Rubino, Carel W le Roux, Stefan Bornstein, Geltrude Mingrone

JournalScan

GI highlights from the literature (5 January, 2023)
Philip J Smith

PostScript

Letter:
Y⁹⁰-radioembolisation in hepatocellular carcinoma induces immune responses calling for early treatment with multiple checkpoint blockers
(4 May, 2022)
Licia Rivoltini, Sherrie Bhoori, Chiara Camisaschi, Laura Bergamaschi, Luca Lalli, Paola Frati, Davide Citterio, Chiara Castelli, Vincenzo Mazzaferro
Letter: Could war and the supply chain crisis affect the sustainability of gastrointestinal endoscopy and single-use endoscopes? (20 April, 2022)
Andrea Sorge, Gian Eugenio Tontini, Lucia Scaramella, Nicoletta Nandi, Flaminia Cavallaro, Maurizio Vecchi, Luca Elli
Letter: Reply to Sachan and Mandavdhare (21 April, 2022)
Sana Fatima Memon, Nitin Jagtap, D Nageshwar Reddy
Letter: Modelling chronic pancreatitis as a complex genetic disease in mice (16 May, 2022)
Zsanett Jancsó, Alexandra Demcsák, Miklós Sahin-Tóth
Letter: Withdrawal of the British Society of Gastroenterology IBD risk grid for COVID-19 severity (5 May, 2022)
Charlie W Lees, Tariq Ahmad, Christopher Andrew Lamb, Nick Powell, Shahida Din, Rachel Cooney, Nicholas A Kennedy, Rachel Ainley, Ruth Wakeman, Christian Philipp Selinger

Editor’s quiz: GI snapshot

White small bowel in a patient with chronic diarrhoea (15 December, 2021)
Charles Houdeville, Suzanne Chartier, Matthieu Delaye, Bettina Fabiani, Nicolas Stocker, Xavier Dray

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Table of contents

February 2023 - Volume 72 - 2

Commentaries

Endoscopy news

Stomach

GI cancer

Inflammatory bowel disease

COVID-19

Endoscopy

Gut microbiota

Colon

Pancreas

Hepatology

JournalScan

PostScript

Editor’s quiz: GI snapshot

Issue Information

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Table of contents

February 2023 - Volume 72 - 2

Commentaries

Endoscopy news

Stomach

GI cancer

Inflammatory bowel disease

COVID-19

Endoscopy

Gut microbiota

Colon

Pancreas

Hepatology

JournalScan

PostScript

Editor’s quiz: GI snapshot

Issue Information