Footnotes

• Contributors MC: writing and drafting the article, critical appraisal and final approval of the manuscript. JDS: critical appraisal and final approval of the manuscript. PB and TRS: acquisition of biopsy image, appraisal and final approval of the manuscript. MG: conception of report, acquisition of data, writing and drafting the article, critical appraisal and final approval of the manuscript.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests MC and PB: none. JDS: support for attending meetings: Pfizer for virtual conference fees. TRS: paid lectures and workshops for Bayer and Siemens. MG: grants or contracts: Pharmacosmos, Janssen and Celltrion, consulting fees: Pfizer and Pharmacosmos, payment of lectures and presentations: Dr Falk, Abbvie, Pharmacosmos, Pfizer and Janssen and support for attending meetings: Pharmacosmos, Pfizer, Abbvie and Janssen.

• Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

• Provenance and peer review Not commissioned; externally peer reviewed.