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Letter
Atrophic autoimmune gastritis: ‘a muddled or misguided core concept compromises our overall comprehension of the problem’
  1. Massimo Rugge1,2,
  2. Robert M Genta3,
  3. Peter Malfertheiner4,
  4. David Y Graham5
  1. 1 Department Medicne - DIMED, Universita degli Studi di Padova, Padova, Italy
  2. 2 Department of Medicine, Baylor College of Medicine Department of Medicine, Houston, Texas, USA
  3. 3 Pathology, Veterans Affairs North Texas Health Care System, Dallas, USA, Irving, Texas, USA
  4. 4 München, Otto-von-Guericke University Magdeburg, Magdeburg, Germany
  5. 5 Medicine (111D), Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas, USA
  1. Correspondence to Professor Massimo Rugge, Department Medicne - DIMED, Universita degli Studi di Padova Dipartimento di Medicina, Padova 35128, Italy; massimo.rugge{at}unipd.it

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We thank Lahner et al for their interest in our study: considering their extensive experience in the field of gastric autoimmunity, their contribution is particularly welcome.1

Overall, most of the authors’ comments are in keeping with the established knowledge of autoimmune gastritis and, therefore, not debatable. We also agree with the interesting citation from Jan Aart Scholte’s work on global governance, which can be applied to any field of science: ‘Definition is not everything, but everything involves definition… A muddled or misguided core concept compromises our overall comprehension of the problem.’ We shall, therefore, start from discussing definitions.

In 2002, an international group of gastrointestinal pathologists (which included Correa) slightly modified the original Correa’ definition and redefined atrophy …

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Footnotes

  • Contributors All authors have been personally involved in the manuscript’s conceptualisation.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.