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Inflammatory bowel disease
Original research
Alzheimer’s disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis

Authors

  • Lena Erkert Department of Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen-Nürnberg, Germany PubMed articlesGoogle scholar articles
  • Reyes Gamez-Belmonte Department of Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen-Nürnberg, Germany PubMed articlesGoogle scholar articles
  • Melanie Kabisch Department of Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen-Nürnberg, Germany PubMed articlesGoogle scholar articles
  • Lena Schödel Department of Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen-Nürnberg, Germany PubMed articlesGoogle scholar articles
  • Jay V Patankar Department of Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen-Nürnberg, GermanyDeutsches Zentrum Immuntherapie (DZI), Erlangen, Germany PubMed articlesGoogle scholar articles
  • Miguel Gonzalez-Acera Department of Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen-Nürnberg, Germany PubMed articlesGoogle scholar articles
  • Mousumi Mahapatro Department of Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen-Nürnberg, Germany PubMed articlesGoogle scholar articles
  • Li-Li Bao Department of Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen-Nürnberg, Germany PubMed articlesGoogle scholar articles
  • Christina Plattner Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria PubMed articlesGoogle scholar articles
  • Anja A Kühl iPATH.Berlin, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany PubMed articlesGoogle scholar articles
  • Jie Shen Department of Neurology, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Lutgarde Serneels VIB Center for Brain and Disease Research, KU Leuven, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Bart De Strooper VIB Center for Brain and Disease Research, KU Leuven, Leuven, BelgiumUK Dementia Research Institute@UCL, University College London, London, UK PubMed articlesGoogle scholar articles
  • TRR241 IBDome Consortium
    Google scholar articles
  • Markus F Neurath Department of Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen-Nürnberg, GermanyDeutsches Zentrum Immuntherapie (DZI), Erlangen, Germany PubMed articlesGoogle scholar articles
  • Stefan Wirtz Department of Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen-Nürnberg, GermanyDeutsches Zentrum Immuntherapie (DZI), Erlangen, Germany PubMed articlesGoogle scholar articles
  • Christoph Becker Department of Medicine 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen-Nürnberg, GermanyDeutsches Zentrum Immuntherapie (DZI), Erlangen, Germany PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Christoph Becker, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; christoph.becker{at}uk-erlangen.de
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Citation

Erkert L, Gamez-Belmonte R, Kabisch M, et al
Alzheimer’s disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis
Gut 2024;73:1618-1631.

Publication history

  • Received November 24, 2023
  • Accepted April 16, 2024
  • First published April 29, 2024.
Online issue publication 
September 09, 2024

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© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.