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Letter
Practical approach to interpretation of 48-hour wireless pH-monitoring studies
  1. Amrit K Kamboj,
  2. Yin Chan,
  3. Jason Nasser,
  4. Jane E Lim,
  5. Bianca W Chang,
  6. Ali Rezaie
  1. Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California, USA
  1. Correspondence to Dr Amrit K Kamboj, Gastroenterology and Hepatology, Cedars-Sinai Medical Center, Los Angeles, California, USA; Amrit.Kamboj{at}cshs.org

https://doi.org/10.1136/gutjnl-2023-331400

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    We have read with great interest the recently published Lyon Consensus 2.0 in Gut, which provides updates to the modern diagnosis of gastro-oesophageal reflux disease (GORD).1 GORD is one of the most common GI disorders affecting nearly a quarter of individuals in the USA.2 3 As symptoms alone are not sufficient to establish a diagnosis of conclusive GORD, objective testing with an esophagogastroduodenoscopy (EGD) and/or pH monitoring is often recommended prior to initiating long-term acid suppression.1 4

    Prolonged wireless pH-monitoring off acid suppression for up to 96 hours is often recommended as the preferred testing modality for unproven GORD as it better accounts for day-to-day variability in oesophageal acid exposure and may be better tolerated than 24-hour …

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    Footnotes

    • Contributors AKK, AR: study concept and design; data analysis and interpretation; drafting of the manuscript; critical revision of the manuscript for important intellectual content. YC, JN, JEL, BWC: drafting of the manuscript; critical revision of the manuscript for important intellectual content.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; internally peer reviewed.